The Clinical Feature of Ulcer Base Over Time After Prophylactic Argon Plasma Coagulation in Colonic EMR

Completed

• Conditions: Gastrointestinal Hemorrhage

• Registration Number: NCT02025764
• Lead Sponsor: Soonchunhyang University Hospital

Brief Summary

The prophylactic APC right after colonic EMR doesn't mean the complete coagulation of visible vessel because of injection material.

The aim of this study was to evaluate the clinical feature of the visible vessels in ulcer base over time after prophylactic APC in colonic EMR.

Detailed Description

The prophylactic Argon plasma coagulation (APC) of non-bleeding visible vessels seems not to have an additional advantage in the prevention of delayed post polypectomy bleeding in recently studies. However, immediate APC after endoscopic mucosal resection (EMR) may not mean the complete coagulation of exposed vessels because of injection material. The aim of this study was to evaluate the clinical feature of the exposed vessels in ulcer base over time after prophylactic APC in colonic EMR. Methods: This study was designed as a prospective study. Investigators excluded diminutive polyp, large polyp (\> 2cm), long stalk pedunculated polyp, and clear ulcer base after EMR. Between August 2013 and May 2014, patients who were enrolled underwent prophylactic APC for non-bleeding visible vessels after colonic endoscopic mucosal resection. After checking the complete coagulation of visible vessels, the numbers of visible vessel group were counted by lap of time such as 1, 3, 5, and 7 min in ulcer base.

Study Timeline

• Study Start: 2013-08
• Primary Completion: 2013-11
• Study Completion: 2013-11
• Study First Submitted: 2013-12-10
• Study First Submitted QC: 2013-12-29
• Study First Posted: 2014-01-01
• Status Verified: 2014-06
• Last Update Submitted: 2014-06-20
• Last Update Posted: 2014-06-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Underwent prophylactic APC for non-bleeding visible vessels after colonic endoscopic mucosal resection.

Exclusion Criteria

• Diminutive polyp, large polyp (> 2cm), long stalk pedunculated polyp, and clear ulcer base after EMR.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
underwent prophylactic APC for non-bleeding visible vessels after colonic endoscopic mucosal resection. After checking the complete coagulation of visible vessels, the numbers of visible vessel group were counted in ulcer base.	4 months

Trial Locations

Locations (1)

Soon Chun Hyang University Hospital Cheonan; 🇰🇷 Cheonan, Chungcheonam-do, Korea, Republic of