The Hematologic Impact of Umbilical Cord Milking Versus Deferred Cord Clamping in Premature Neonates. A Randomized Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Delayed Cord Clamping
- Sponsor
- Zagazig University
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- hematological parameters of the premature neonates
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
Comparing the beneficial effect of cord milking versus deferred cord clamping in preterm neonates. A randomized controlled trial
Detailed Description
Placental transfusion either by deferred cord clamping or umbilical cord milking became standard care and recommended management especially in preterm deliveries.1 In average, about 80 ml of blood was found to be transferred to the neoborn by one minute after birth.2 This additional blood can afford extra iron and blood volume giving the benefit of less iron deficiency anemia during the first year of life, less need for blood transfusion, less need for vasopressors and less intraventricular hemorrhage (IVH) by 50%.3 Placental transfusion with different techniques proved safety with no significant risks regarding postpartum hemorrhage, polycythemia, jaundice, Apgar score or admission rates.4 Our study aims to compare delayed cord clamping with umbilical cord milking as the best way for placental transfusion for preterm neonates.
Investigators
Hytham Atia
lecturer
Zagazig University
Eligibility Criteria
Inclusion Criteria
- •Gestational age 24 to 34+6 weeks
Exclusion Criteria
- •Category III CTG
- •Monochorionic twins
- •Significant antepartum hemorrhage
- •IUGR or Rh incompatibility
Outcomes
Primary Outcomes
hematological parameters of the premature neonates
Time Frame: 12 months
first draw and peak hematocrit value and hemoglobin percent, need for inotropes and blood transfusion
Secondary Outcomes
- composite neonatal morbidities(12 month)