The Hematologic Impact of Umbilical Cord Milking Versus Deferred Cord Clamping in Premature Neonates. A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 2
- 主要终点
- hematological parameters of the premature neonates
研究概览
简要总结
Comparing the beneficial effect of cord milking versus deferred cord clamping in preterm neonates. A randomized controlled trial
详细描述
Placental transfusion either by deferred cord clamping or umbilical cord milking became standard care and recommended management especially in preterm deliveries.1 In average, about 80 ml of blood was found to be transferred to the neoborn by one minute after birth.2 This additional blood can afford extra iron and blood volume giving the benefit of less iron deficiency anemia during the first year of life, less need for blood transfusion, less need for vasopressors and less intraventricular hemorrhage (IVH) by 50%.3 Placental transfusion with different techniques proved safety with no significant risks regarding postpartum hemorrhage, polycythemia, jaundice, Apgar score or admission rates.4 Our study aims to compare delayed cord clamping with umbilical cord milking as the best way for placental transfusion for preterm neonates.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
盲法说明
closed envelop method
入排标准
- 年龄范围
- 24 Weeks 至 35 Weeks(Child)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Gestational age 24 to 34+6 weeks
排除标准
- •Category III CTG
- •Monochorionic twins
- •Significant antepartum hemorrhage
- •IUGR or Rh incompatibility
结局指标
主要结局
hematological parameters of the premature neonates
时间窗: 12 months
first draw and peak hematocrit value and hemoglobin percent, need for inotropes and blood transfusion
次要结局
- composite neonatal morbidities(12 month)
研究者
Hytham Atia
lecturer
Zagazig University
