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临床试验/NCT03147846
NCT03147846已完成不适用

The Hematologic Impact of Umbilical Cord Milking Versus Deferred Cord Clamping in Premature Neonates. A Randomized Controlled Trial

Zagazig University2 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2017年6月8日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
200
试验地点
2
主要终点
hematological parameters of the premature neonates

研究概览

简要总结

Comparing the beneficial effect of cord milking versus deferred cord clamping in preterm neonates. A randomized controlled trial

详细描述

Placental transfusion either by deferred cord clamping or umbilical cord milking became standard care and recommended management especially in preterm deliveries.1 In average, about 80 ml of blood was found to be transferred to the neoborn by one minute after birth.2 This additional blood can afford extra iron and blood volume giving the benefit of less iron deficiency anemia during the first year of life, less need for blood transfusion, less need for vasopressors and less intraventricular hemorrhage (IVH) by 50%.3 Placental transfusion with different techniques proved safety with no significant risks regarding postpartum hemorrhage, polycythemia, jaundice, Apgar score or admission rates.4 Our study aims to compare delayed cord clamping with umbilical cord milking as the best way for placental transfusion for preterm neonates.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Prevention
盲法
Double (Participant, Outcomes Assessor)

盲法说明

closed envelop method

入排标准

年龄范围
24 Weeks 至 35 Weeks(Child)
性别
All
接受健康志愿者

入选标准

  • Gestational age 24 to 34+6 weeks

排除标准

  • Category III CTG
  • Monochorionic twins
  • Significant antepartum hemorrhage
  • IUGR or Rh incompatibility

结局指标

主要结局

hematological parameters of the premature neonates

时间窗: 12 months

first draw and peak hematocrit value and hemoglobin percent, need for inotropes and blood transfusion

次要结局

  • composite neonatal morbidities(12 month)

研究者

申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Hytham Atia

lecturer

Zagazig University

研究点 (2)

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