Screening of Patients With Rheumatoid Arthritis for Interstitial Lung Disease
- Conditions
- Rheumatoid ArthritisInterstitial Lung Disease
- Registration Number
- NCT05391100
- Lead Sponsor
- Polyclinic of the Hospitaller Brothers of St. John of God, Budapest
- Brief Summary
The quantitative and qualitative analysis of RA lung involvement in the Hungarian population
- Detailed Description
Interstitial lung disease (ILD) accounts for a significant proportion of mortality and morbidity in rheumatoid arthritis (RA). The aim of this prospective longitudinal study is to asess the interstitial lung involvement in Hungarian rheumatoid arthritis patients. Laboratory markers, X-ray based imaging methods, pulmonological functional tests, QOL questionnaire and sleep quality assessement questionnaire are used to estimate the interstitial lung disease. Also smaller cross-sectional studies about the imaging parameters and a national register is planned to be created based on these data.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 500
- diagnosis of RA
- pregnancy, breastfeeding
- previous diagnosis of ILD, lung cancer, registered lung infection in the last 2 months
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method pattern of ILD From baseline to at least 5 years to characterize the ILD patterns based on imaging methods
Prevalence of ILD From baseline to at least 5 years detection of ILD with imaging methods
- Secondary Outcome Measures
Name Time Method Correlation with biomarkers From baseline to at least 2 years correlation of the imaging results with respiratory function, disease activity and laboratory markers
Trial Locations
- Locations (3)
Department of Pulmonology, Semmelweis University Faculty of Medicine
🇭🇺Budapest, Hungary
Medical Imaging Centre, Semmelweis University
🇭🇺Budapest, Hungary
Buda Hospital of the Hospitaller Order of Saint John of God
🇭🇺Budapest, Hungary