Effect of bitter almond oil in treatment of knee arthrosis
- Conditions
- Osteoarthritis.Arthrosis, unspecified
- Registration Number
- IRCT20170821035817N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 200
Male or female patients with 1 or 2 knees osteoarthritis according to the American College of Rheumatology criteria after physical examination and knee joint radiography
Age of 40 to 85 years
Flare of the disease after oral non-steroidal anti-inflammatory drug or acetaminophen discontinuation which have been used at least 3 days a week during the past month (flare means increase of at least 2 scores in the total pain subscale score in the beginning of the study.)
Western Ontario and McMaster Universities (WOMAC) pain subscale index at least 9 out of 20 in the beginning of the study
Secondary osteoarthritis (due to a definite disease)
Arthroscopy
Knee surgery
History of knee replacement surgery
Infection
Cardiovascular disease
Hepatic disease
Renal disease
Other chronic inflammatory disease
History of alcohol abuse
History of drug abuse
History of narcotic abuse
Skin disease in the knee area
Fibromyalgia
Debilitating disease affecting the knee
Pregnant women
Women planning pregnancy
Lactating women
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Extent of arthritis. Timepoint: Before intervention and 1 month after intervention. Method of measurement: The Western Ontario and McMaster Universities Arthritis Index questionnaire.
- Secondary Outcome Measures
Name Time Method Extent of joint stiffness. Timepoint: Before intervention and 1 month after intervention. Method of measurement: The Western Ontario and McMaster Universities Arthritis Index questionnaire.;Extent of joint pain. Timepoint: Before intervention and 1 month after intervention. Method of measurement: The Western Ontario and McMaster Universities Arthritis Index questionnaire.;Extent of physical function. Timepoint: Before intervention and 1 month after intervention. Method of measurement: The Western Ontario and McMaster Universities Arthritis Index questionnaire.