Efficacy of dual parenteral artemisinin-based combination therapy for cerebral malaria in a randomized control trial in Nigerian children.
Not Applicable
Not yet recruiting
- Conditions
- Malaria
- Registration Number
- PACTR202102893629864
- Lead Sponsor
- Alao Michael and Co Authors
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 359
Inclusion Criteria
1.Children between the ages of 6 months to 17 years as at the last birthday
2.Children with unarousable coma lasting more than 30 minutes in the presence of demonstratable peripheral asexual P. falciparum parasitemia.
3.Children who develop deterioration in their level of consciousness after admission and demonstrate asexual Plasmodium falciparum in the peripheral blood.
Exclusion Criteria
1.Children with positive biochemical and/or microbiological CSF result consistent with a diagnosis of meningitis
2.Children who have intracranial infections or intracranial space-occupying lesions
3.Children with previous neurological deficit either focal or global
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method