TCTR20230202004
Unknown
Phase 3
The study of effectiveness of platelet-rich plasma (PRP) treatment for lichen planus pigmentosus (pilot study)
Institute of dermatology0 sites15 target enrollmentFebruary 2, 2023
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- ichen planus pigmentosus
- Sponsor
- Institute of dermatology
- Enrollment
- 15
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients who were diagnosed with lichen planus pigmentosus, age 18 \- 60 years
- •2\. Has facial LPP lesion for at least 6 months
- •3\. Histology confirmed LPP as evidenced by perivascular infiltrate, lichenoid reaction, melanophages and pigment pigmentation (melanin) accumulates under the epidermis and dermis.
- •4\. Patch test result is negative
Exclusion Criteria
- •1\. Patients who are pregnant or breastfeeding
- •2\. Patients with a history of keloids, hypertrophic scars, herpes virus infection or skin disease around the lesion
- •3\. Patients with blood disorders, liver disease or patients receiving chemotherapy/ anticoagulants
- •4\. Patients with hyperpigmentation from other conditions, such as pigmented contact dermatitis, with positive patch test results, fixed drug eruption, lichenoid drug reaction, ochronosis, melasma, PIH, endocrinopathies, etc.
- •5\. Patients with a history of treatment using topical bleaching agents and lasers within 6 months prior to study participation.
Outcomes
Primary Outcomes
Not specified
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