A Participant Rotation Magnetic Resonance Imaging Study

Not Applicable

• Conditions: Any Cancer; Cancer - Any cancer

• Registration Number: ACTRN12618000676213
• Lead Sponsor: iverpool Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-04-26
• Study Completion: 2021-05-17
• Last Update Posted: 6 June 2022

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

1.Greater than or equal to 18 years of age
2.Willing and able to comply with all study requirements
3.Must be able to read and understand English
4.Signed, written informed consent
5.Must fall within height of 190cm, width and depth of 32cm x 45cm and weight limits of 100kg max the participant rotation system
6. Completed MRI safety screening form

Inclusion Criteria for Cancer Participant Volunteers
1.A current or previous diagnosis of cancer, any stage
2.Must have sufficient mobility to get into/out of the participant rotation system, as determined by the clinical investigator
3.Currently or previously being treated with radiotherapy

Inclusion Criteria for Healthy Volunteers
1.Current Staff member of Liverpool Hospital or Ingham Institute or University Student

Exclusion Criteria

1.Pregnant women
2.Mentally impaired participants or participants for whom attaining informed consent would be difficult (including language barriers)
3.Unable to undergo an MRI examination or has MRI contraindications
4.Participants who have been clinically diagnosed with severe claustrophobia

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Internal organ motion assessed by automated segmentation methods and structure comparison metrics including the dice similarity coefficient, volume, Hausdorff distance and centroid positions. [Approximately 1 week after image analysis];Internal organ deformation assessed by automated segmentation methods and structure comparison metrics including the dice similarity coefficient, volume, Hausdorff distance and centroid positions. [Approximately 1 week after image analysis]

Secondary Outcome Measures

Name	Time	Method
To assess participant acceptance of rotation within an MRI imaging system.This outcome will be assessed by analysing the completed CLQ, STAI, FMS and Participant comfort questionnaires conducted pre and post imaging.[After focus group sessions occurring 1 month after MRI];To assess participant safety and efficacy of rotation within an MRI imaging system.This outcome will be assessed by analysing the completed CLQ, STAI, FMS and Participant comfort questionnaires conducted pre and post imaging.[After focus group sessions occurring 1 month after MRI]