Follow-up GEEF-study: Behavioral development, school performance, neurocognitive functioning and brain development of very premature (<32 weeks) and/or very low birth weight (<1500 grams) children at school-age, with or without glutamine suppletion after birth
Completed
- Conditions
- immature brain development caused by preterm birthPrematurity1004225810028920
- Registration Number
- NL-OMON33479
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 170
Inclusion Criteria
Participation with the original GEEF-study (which had the inclusioncriteria: <32 weeks of gestation and/or lower than 1500 grams birth weight).
Exclusion Criteria
Deafness or Blindness, which will make the assessment of neuropsychological tasks impossible
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Differences as measured by neurocognitive assessment, behavioural and emotional<br /><br>questionnaires, and school performance. Furthermore, differences in brain<br /><br>structure as determined by sMRI (volumetric parameters of white and grey<br /><br>matter) fMRI (BOLD-signal changes) and DTI (FA-value indicating white matter<br /><br>integrity). </p><br>
- Secondary Outcome Measures
Name Time Method <p>Not applicable</p><br>