Faecal inflammatory markers after bariatric surgery

Completed

• Conditions: gastric bypass; 10017969

• Registration Number: NL-OMON42770
• Lead Sponsor: Slotervaartziekenhuis

Brief Summary

Trial is onging in other countries

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-10-01
• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 41

Inclusion Criteria

Patients who will undergo either a RYGB or sleeve gastrectomy.

Exclusion Criteria

- Diarrhea at the time of faeces collection
- Useage of NSAID and unable tot stop for at least 5 days prior to faeces collection.
- Unable to fill out questionares because of linguistic difficulties
- An acute gastrointestinal disease at the time of participation or chronic gastrointestinal disease in the medical history

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary outcome is the concentration and progression over time of the faecal<br /><br>inflammatory markers calprotectin, lactoferrin and calgranulin C, before and<br /><br>until 1 year after RYGB.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcomes<br /><br>- Secondary outcome is the difference between concentrations of calprotectin,<br /><br>lactoferrin and calgranulin-C after RYGB or sleeve gastrectomy<br /><br>- Another outcome is the correlation between GSRS scores and concentration of<br /><br>faecal inflammatory markers after bariatric surgery </p><br>