A Prospective Observational Study To Analyse The Efficacy Of RENAL ANGINA INDEX In Predicting The Course Of ACUTE KIDNEY INJURY In Critically Ill Adult Patients
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Use of Renal Angina Index to predict the course of Acute Kidney Injury
研究概览
简要总结
AKI can increase the risk of Chronic Kidney Disease through a number of mechanisms that lead to tubulointerstitial damage and fibrosis. Hence Timely Diagnosis and Timely management can save the nephrons from going for a irreversible injury leading to Chronic Kidney Disease. Recently, the Renal angina index (RAI), which is determined based on changes in renal function, was proposed to risk stratify critically ill children at high risk of AKI.The concept of renal angina has come into use to highlight the characteristics of renal injury as an analogy to the concept of angina pectoris, which is used to increase the suspicion of acute coronary syndrome in cardiology. The RAI is assumed to serve as a potential biomarker for detecting early signs of persistent AKI for 1 week. The RAI in adults was proposed.In our study we want to analyse the efficacy of Renal Angina Index in early prediction of AKI , so that Nephroprotective measures can be initiated early to prevent the further Renal injury. In our Study , we have hypothesized that Renal Angina Index more than 8 does not correlate with Acute Kidney Injury in critically ill adult patients.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)(—)
- 性别
- All
入选标准
- •Patient admitted to ICU for more than 24 hours.
排除标准
- •Presence of AKI on admission Serum Creatinine more than 2.5mg/dl on admission Patients already on Renal Replacement Therapy Chronic Kidney Disease History of Kidney Transplantation Pregnant patient.
结局指标
主要结局
Use of Renal Angina Index to predict the course of Acute Kidney Injury
时间窗: Day 0,1,3,7
次要结局
- Analysing the Role of Renal Angina Index in predicting progression to Acute Kidney Disease and requirement of Renal Replacement Therapy(To study the correlation between Renal Angina Index Value and stage of AKI as per KDIGO guidelines)
研究者
Dr Preethi Rajsri Anandhan
Meenakshi Mission Hospital & Research Centre
