Hot Snare Versus Hot Snare Polypectomy With Saline Injection for Colorectal Polyps

Not Applicable

Completed

• Conditions: Polyp of Large Intestine
• Interventions: Procedure: hot snare polypectomy; Procedure: hot snare polypectomy after saline injection

• Registration Number: NCT02239536
• Lead Sponsor: Bo-In Lee

Brief Summary

The complete removal of colorectal polyp is required to prevent tumor recurrence and development of potential interval cancers. However, several studies have shown high incomplete resection rate in endoscopic removal of neoplastic colorectal polyps larger than 5 mm. The polypectomy techniques using hot snare are usually used for the removal of these polyps. However, the optimal technique for complete resection of these polyps is unknown. There are few data comparing hot snare polypectomy with hot snare polypectomy after saline injection for complete resection of colorectal polyps (5mm or larger). The aim of this study is to compare hot snare polypectomy with hot snare polypectomy after saline injection for removal of 5-10mm sized colorectal polyps.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-06
• Study First Submitted: 2014-09-10
• Study First Submitted QC: 2014-09-10
• Study First Posted: 2014-09-12
• Primary Completion: 2017-12
• Study Completion: 2018-02
• Results First Submitted: 2019-07-17
• Status Verified: 2020-04
• Results First Submitted QC: 2020-04-06
• Last Update Submitted: 2020-04-06
• Results First Posted: 2020-04-14
• Last Update Posted: 2020-04-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 362

Inclusion Criteria

• Patients over the age of 30
• 5~10mm sized colorectal polyps
• Informed consent

Exclusion Criteria

• Inflammatory bowel diseases (Crohn's disease, or ulcerative colitis)
• Patient undergoing antiplatelets (aspirin, clopidogrel and others) or anticoagulant therapy
• ASA class III or more
• Any condition which, in the opinion of the Investigator, places the patient at unacceptable risk if he/she were to participate in the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Hot snare polypectomy	hot snare polypectomy	Intervention: Procedure: removal of eligible polyps using hot snare polypectomy technique
Hot snare polypectomy(saline injection)	hot snare polypectomy after saline injection	Intervention: Procedure: removal of eligible polyps using hot snare polypectomy after saline injection technique

Primary Outcome Measures

Name	Time	Method
Complete Resection Rate	2 weeks after	Complete resection was defined as the absence of residual polyp in the resection margin

Secondary Outcome Measures

Name	Time	Method
Lateral Margin	2 weeks after	Observation of maring on a recsected specimen

Trial Locations

Locations (1)

Division of Gastroenterology; Seoul St. Mary's hospital; 🇰🇷 Seoul, Korea, Republic of