Thioguanine Suppositories For Proctitis

Phase 1

• Conditions: inflammatory bowel disease (IBD); proctitis; Oral and Gastrointestinal - Inflammatory bowel disease

• Registration Number: ACTRN12616000602426
• Lead Sponsor: Mater Hospital Brisbane

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-05-10
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

1.Patients to include in the study will be screened from:
a.Patients attending Gastroenterology outpatient clinics.
b.Pre-existing clinical databases in the department of Gastroenterology and Dr Florin’s private rooms at Mater Health Services, South Brisbane.

2.All patients satisfying the criteria for severe proctitis will be screened and will need to meet the below inclusion and exclusion criteria.
a) Able to give informed consent
b) Age 18 and above
c) Clinical evidence of severe proctitis: Established diagnosis of severe Proctitis (isolated proctitis proven at a colonoscopy within 3 months of consenting and with Mayo endoscopic subscore greater than or equal to 2.)
AND
d) patients who have failed the ‘standard’ combination of oral and rectal 5-ASA at the time of the consenting process as demonstrated by a partial Mayo Score greater than 3 while on standard treatment.

Exclusion Criteria

Pregnant women

Study & Design

• Study Type: Interventional
• Study Design: Not specified