Functional Energetics and Imaging for Phenotypic Characterization of Patients at Risk for Sudden Cardiac Death

Johns Hopkins University1 site in 1 country400 target enrollmentOctober 1, 2003

ConditionsSudden Cardiac Death

Overview

Phase: N/A
Intervention: Not specified
Conditions: Sudden Cardiac Death
Sponsor: Johns Hopkins University
Enrollment: 400
Locations: 1
Primary Endpoint: sudden cardiac death
Status: Recruiting
Last Updated: 3 months ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Sudden cardiac death is a tragic event that strikes all age groups and is unfortunately increasing in prevalence. Because it is difficult to predict those at highest risk, this study is designed to test the hypothesis that new imaging techniques (magnetic resonance imaging [MRI] and computed tomography [CT]) are useful for identifying factors which put people at high risk for sudden death.

Detailed Description

Some people with heart disease and a weak heart muscle experience abnormal electrical activity of the heart that may predispose them to sudden death. In light of this risk, it has been recommended that such patients undergo implantation of an implantable cardioverter defibrillator (ICD). Your doctors have determined that you are such a patient and are to undergo implantation of an ICD. It is unclear who among the many patients who undergo ICD implantation for this reason are at greatest risk of sudden death and therefore require electrical response from their ICD. This research is being done to determine whether new imaging tests, such as magnetic resonance imaging (MRI) or multi-detector computed tomography (MDCT), can be used to predict who is at highest risk of sudden death and require electrical response from their ICD.

Registry

clinicaltrials.gov

Start Date

October 1, 2003

End Date

July 1, 2029

Last Updated

3 months ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Johns Hopkins University

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Left ventricular ejection fraction \<or = 35%
•Planned implantable cardioverter-defibrillator (ICD) implantation for clinical indications (primary prevention)