Bone Mineral Density in the Korean Patients With Chronic Schizophrenia With Alcohol Abuse
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- The change of bone mineral density
研究概览
简要总结
People with chronic mental disorder such as schizophrenia and alcohol abuse are high risk groups for developing osteoporosis.
To evaluate the prevalence of bone mineral density in men patients with schizophrenia with alcohol abuse, the investigators will compare bone mineral density between patient with schizophrenia with and without alcohol abuse.
详细描述
People with schizophrenia has been known as a high risk groups for developing osteoporosis, because of lack of exercise, poor nutrition and high rate of smoking. Those with alcohol abuse may be higher risk group than one with schizophrenia without alcohol abuse, because they frequently have several medical problems such as liver dysfunction, Vitamin D deficiency, hyperparathyroidism and those medical condition increase risk for developing osteoporosis. Also alcohol itself can increase bone loss too by disturbing bone remodeling and enhancing bone fragility. To compare the prevalence of bone mineral density in patients with schizophrenia with alcohol abuse to those without alcohol problem, we will investigate BMD in large population of Korean patients with those illnesses.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •DSM-IV diagnosis of schizophrenia
- •Onset of illness more than 5 years.
排除标准
- •No severe Medical and endocrinological disorder
结局指标
主要结局
The change of bone mineral density
时间窗: cross sectional and prospective
次要结局
- The effects of Smoking and antipsychotic drug on BMD(Cross sectional Study)