Bone Density in Patients With Schizophrenia

Completed

• Conditions: Schizophrenia; Alcohol Abuse
• Interventions: Other: No Intervention

• Registration Number: NCT00540267
• Lead Sponsor: Inje University

Brief Summary

People with chronic mental disorder such as schizophrenia and alcohol abuse are high risk groups for developing osteoporosis.

To evaluate the prevalence of bone mineral density in men patients with schizophrenia with alcohol abuse, the investigators will compare bone mineral density between patient with schizophrenia with and without alcohol abuse.

Detailed Description

People with schizophrenia has been known as a high risk groups for developing osteoporosis, because of lack of exercise, poor nutrition and high rate of smoking. Those with alcohol abuse may be higher risk group than one with schizophrenia without alcohol abuse, because they frequently have several medical problems such as liver dysfunction, Vitamin D deficiency, hyperparathyroidism and those medical condition increase risk for developing osteoporosis. Also alcohol itself can increase bone loss too by disturbing bone remodeling and enhancing bone fragility. To compare the prevalence of bone mineral density in patients with schizophrenia with alcohol abuse to those without alcohol problem, we will investigate BMD in large population of Korean patients with those illnesses.

Study Timeline

• Study First Submitted: 2007-10-04
• Study First Submitted QC: 2007-10-04
• Study First Posted: 2007-10-05
• Study Start: 2007-11
• Status Verified: 2008-10
• Primary Completion: 2008-11
• Study Completion: 2008-11
• Last Update Submitted: 2008-11-03
• Last Update Posted: 2008-11-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• DSM-IV diagnosis of schizophrenia
• Onset of illness more than 5 years.

Exclusion Criteria

• No severe Medical and endocrinological disorder

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Schizophrenia	No Intervention	Chronic schizophrenia with aged 18-80 years

Primary Outcome Measures

Name	Time	Method
The change of bone mineral density	cross sectional and prospective

Secondary Outcome Measures

Name	Time	Method
The effects of Smoking and antipsychotic drug on BMD	Cross sectional Study

Trial Locations

Locations (1)

Joo-Cheol Shim; 🇰🇷 Busan, Korea, Republic of