Effects of Omega-3 Fatty Acids and Menaquinone-7 on Thrombotic Tendency
Not Applicable
Completed
- Conditions
- Atherosclerosis
- Registration Number
- NCT00732576
- Lead Sponsor
- Maastricht University Medical Center
- Brief Summary
Omega-3 fatty acids are notably present in fish oil and krill oil, and are known to have beneficial effects on the vasculature. Vitamin K2 is known for preventing vascular calcification. In this study we investigate a potential synergy between the effects of either fish or krill oil and menaquinone-7, which is one of K2 vitamins.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 57
Inclusion Criteria
- Healthy subjects - BMI < 30
- written informed consent
Exclusion Criteria
- Use of oral anticoagulants
- Coagulation disorders
- Use of multivitamin supplements
- Use of corticosteroids, anticonceptives
- hypertriglyceridemia, hypercholesterolemia
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Endogenous Thrombin Potential (ETP) 12 weeks
- Secondary Outcome Measures
Name Time Method Osteocalcin carboxylation 12 weeks Matrix Gla-protein carboxylation 12 weeks
Trial Locations
- Locations (1)
VitaK - Maastricht University
🇳🇱Maastricht, Netherlands
VitaK - Maastricht University🇳🇱Maastricht, Netherlands