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临床试验/CTRI/2025/01/078852
CTRI/2025/01/078852尚未招募不适用

Comparative evaluation of resin based sealant & silver nanocrystals incorporated sealant on permanent molars in children A randomized controlled trial

Kidsedental1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年3月12日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
Retention of pit and fissure sealant

研究概览

简要总结

Pit and fissure sealants have been widely used for more than four decades in preventing dental caries.1 The complex morphology of occlusal pits and fissures makes them an ideal site for retention of bacteria and food remnants. The most cariessusceptible period of the first permanent molar is the long eruption phase as the enamel is immature during this period. Resin sealants that possess both low viscosity and excellent wetting properties have been recommended for dental use.2 Silver nanoparticles have recently been shown to possess bactericidal and bacteriostatic properties in various species of microorganisms.3 In dentistry, silver nanoparticles are used to improve the quality of the dental materials for a better treatment outcome.4 It is believed that the success of sealants is assessed by retention rate and caries prevention.5 Thus, the aim of the study is to evaluate and compareclinical efficacy of resin based sealant and silver nanocrystals incorporated sealant on permanent molars in children.

研究设计

研究类型
Interventional
分配方式
Random Number Table
盲法
Not Applicable

入排标准

年龄范围
6.00 Year(s) 至 9.00 Year(s)(—)
性别
All

入选标准

  • Healthy cooperative children with fully erupted permanent molars between the age of 6 to 9 years.
  • Deep pits and fissures are present in these permanent molars (ICDAS II code 00).
  • Initial occlusal carious lesions involving the pits and fissures of enamel (ICDAS II code 01).
  • Incipient carious lesion involving enamel (ICDAS II code 02 and 03).

排除标准

  • •Uncooperative child.
  • •Children whose parents did not give consent for the study.
  • •Children with systemic disorders.

结局指标

主要结局

Retention of pit and fissure sealant

时间窗: 1month, 3 months and 6 months

次要结局

  • If retention is lost then secondary caries will be assessed using an explorer at 1,3 & 6 months(1month, 3 months & 6 months)

研究者

发起方
Kidsedental
申办方类型
Pharmaceutical industry-Indian

研究点 (1)

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