Follow-up examination of cardiac function after liver transplantation using cardiac MRI
Recruiting
- Conditions
- K74Fibrosis and cirrhosis of liver
- Registration Number
- DRKS00029928
- Lead Sponsor
- niversitätsklinikum Hamburg-Eppendorf
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Patients who received an uncomplicated CMRI before the LTX.
Patients who, based on this CMRI, do not have any critical myocardial ischemia relevant to LTX.
Exclusion Criteria
Inability to give informed consent.
Known, general contraindication for an MRI scan, such as the presence of
a cardiac pacemaker or implantable defibrillator, ferromagnetic clips or intracranial clips, shrapnel, etc.,
Acute heart failure > NYHA III and/or rhythmic instability.
Severe renal impairment with a glomerular filtration rate <30 mL/min/1.73 m2.
Serious infectious diseases.
Pregnancy.
Age younger than 18 .
Claustrophobia (fear of confined or confined spaces).
Hypersensitivity to any of the active ingredients used.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ormalization of the left ventricular ejection fraction (EF) as a reference parameter for the<br>cardiac function 6 months after liver transplantation.
- Secondary Outcome Measures
Name Time Method ormalization of strain as a newly established parameter for global and regional deformation<br>the heart muscle fibers.<br>Reduction of the extracellular volume as an indicator for an existing myocardial fibrosis. Occurrence of new, functionally relevant coronary stenoses.