Paracetamol (Acetaminophen) In Stroke.
Recruiting
- Conditions
- stroke
- Registration Number
- NL-OMON25645
- Brief Summary
PAPAS, Dippel, van Breda et al., Stroke 2001 PISA, Dippel, van Breda et al., BMC Cardiovascular Disorders, 2003 PAIS protocol, van Breda, van der Worp et al., BMC Cardiovascular Disorders, 2005
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 2500
Inclusion Criteria
1. Clinical diagnosis of acute stroke
2. Possibility to start treatment within 12 hours from onset
Exclusion Criteria
1. A body temperature lower than 36 degrees Celsius or higher than 39 degrees Celsius
2. A history of liver disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome measure is the dichotomized mRS (¡Ü2: good outcome, ¡Ý3: poor outcome) at 3 months.
- Secondary Outcome Measures
Name Time Method Secondary endpoints are the score on the Barthel index after two weeks, body temperature after 24 hours of treatment, and the EuroQol-5D at 3 months.