“THE STUDY TO EVALUATE THE SUBCLINICAL LOWER EXTREMITY MUSCLE STRENGTH DECREASE IN DIABETIC INDIVIDUAL AND COMPARING WITH AGE MATCHED HEALTHY SUBJECTS INFLUENCING QUALITY OF LIFEâ€.

Diabetes mellitus is a chronic metabolicdisease, characterized by hyperglycemia resulting in insulin secretiondeficits, insulin action or both and highly glycated hemoglobin, higher inelderly than in younger population. Generally skeletal muscle tissue isresponsible for 40% of body weight and considered as major site of insulinmediated glucose uptake, which accounts approximately 75% of whole body insulinstimulated glucose uptake  Therefore decrease inmuscle strength especially in lower limbs is depicted by the insulinresistance, metabolic inflexibility and neuro muscular impairments.Earlier studies have stated that Diabetes mellitus isassociated with loss of muscle strength in distal extremity of lower limb. There is a growing evidences which shows thecomplication of type 2 diabetes may translate into the functional impairment inolder people, this might link the metabolic and mechanical function of the muscle

Henceforth theevaluation of the lower extremity muscle strength can be assessed by hand helddynamometer, for knee extensors, ankle dorsiflexors, plantar flexors, in bothdiabetic and age matched healthy individuals, and to identify the impact ofthese muscles with sit to stand lower extremity functional strength and consideringthe variables like duration of diabetes, glycemic control, HbA1C values.

Boththe group will be evaluated with five repetitionsit to stand test (FRSTST), to screen their lower extremity functional strength,and quality of life measure done through generic health related quality of lifemeasure SF -36 Questionnaire

The main objective of this study is to determinewhether a clinical scenario might exist where there will be a subclinical musclepower decrease without any reflections on functions performed in diabetic individualswhen compared with age matched healthy individuals.