Laryngoscopy and Coronary Artery Bypass Graft Surgery

Not Applicable

Recruiting

• Conditions: Videolaryngoscopy
• Interventions: Other: Tracheal intubation using Storz VL; Other: Tracheal intubation using MacGrath VL; Other: Tracheal intubation using EzVision VL; Other: Tracheal intubation using Macintosh laryngoscopy

• Registration Number: NCT06349005
• Lead Sponsor: Konya Meram State Hospital

Brief Summary

In this prospective, randomized, controlled trial, the purpose is to compare Macintosh laryngoscope, EzVision® video laryngoscope, McGrath® video laryngoscope and Storz® video laryngoscope in terms of hemodynamic response associated with intubation in adult patients undergoing Coronary Artery Bypass Surgery (CABG).

Detailed Description

During endotracheal intubation, laryngoscopy can significantly affect hemodynamic responses, including tachycardia and elevated blood pressure, which may be particularly detrimental to individuals with cardiovascular conditions. Various studies have explored the hemodynamic reactions associated with laryngeal stimulation through different intubation devices. Researchers hypothesize that endotracheal intubation using video laryngoscopy will elicit a reduced hemodynamic response compared to traditional (Macintosh) laryngoscopy. In this prospective and randomized clinical study, the purpose is to compare the Macintosh laryngoscope, EzVision® video laryngoscope, McGrath® video laryngoscope and Storz® video laryngoscope concerning haemodynamic response associated with intubation in adult patients undergoing Coronary Artery Bypass Surgery (CABG).

Study Timeline

• Study First Submitted: 2024-02-26
• Study First Submitted QC: 2024-03-31
• Study First Posted: 2024-04-05
• Status Verified: 2025-01
• Study Start: 2025-01-12
• Last Update Submitted: 2025-01-12
• Last Update Posted: 2025-01-14
• Primary Completion: 2025-03-01
• Study Completion: 2025-04-10

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 112

Inclusion Criteria

• Age range between 18 and 75 years.
• Scheduled for elective coronary artery bypass surgery.
• Classified under American Society of Anesthesiologists (ASA) physical status II-III.
• Patients with no history of difficult intubation or associated risk factors.

Exclusion Criteria

• Emergency case
• Predicted difficult airways
• Body mass index > 35 kilograms per meter squared
• Baseline hemodynamic instability

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group Storz VL	Tracheal intubation using Storz VL	Patients will undergo intubation with the Storz Videolaryngoscope®, during which their hemodynamic responses will be documented.
Group MacGrath VL	Tracheal intubation using MacGrath VL	Patients will undergo intubation with the McGrath Videolaryngoscope®, during which their hemodynamic responses will be documented.
Group EzVision VL	Tracheal intubation using EzVision VL	Patients will undergo intubation with the EzVision Videolaryngoscope®, during which their hemodynamic responses will be documented.
Group Traditional	Tracheal intubation using Macintosh laryngoscopy	Patients will undergo intubation with the traditional (Macintosh) laryngoscopy, during which their hemodynamic responses will be documented.

Primary Outcome Measures

Name	Time	Method
Hemodynamic response	Change from baseline heart rate at 10 minutes	Change from baseline heart rate

Secondary Outcome Measures

Name	Time	Method
Intubation time	180 seconds	The duration from when the laryngoscope passes through the teeth until it is withdrawn back to the teeth will be measured.
Visualization of the glottis	180 seconds	According to Cormack Lehane classification four grades (1-4). The higher the grade, the higher the likelihood of difficult intubation.

Trial Locations

Locations (2)

Betul Kozanhan; 🇹🇷 Konya, Turkey

Konya City Hospital; 🇹🇷 Konya, Turkey