Pharmacokinetics of broccoli sprout extract in preeclampsia.

Phase 1

Recruiting

• Conditions: Preeclampsia; Reproductive Health and Childbirth - Antenatal care; Reproductive Health and Childbirth - Fetal medicine and complications of pregnancy

• Registration Number: ACTRN12618001655235
• Lead Sponsor: Monash Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-10-08
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 18

Inclusion Criteria

••Singleton pregnancy
•Diagnosis of preeclampsia as defined by the according to the SOMANZ guidelines
•Gestation greater than 24+0 weeks.
•Viable fetus, as determined by the treating obstetrician
•Able to safely continue pregnancy for 48 hours, or longer, as determined by the treating obstetrician
•Normal mid-trimester morphology scan, with no detectable significant anomalies.
•Deemed capable of understanding the information provided and able to give written informed consent (with interpreter use as required).
•>18 years of age
•Clinical hypertension in accordance with SOMANZ guidelines

Exclusion Criteria

•Eclampsia
•Current use of broccoli sprout extract supplement
•Contraindications to use (eg, intolerance of broccoli)
•Significant uncertainty in ensuring gestational age is within limits
•Unwillingness or inability to follow the procedures outlined in the PI and CF
•Mentally, cognitively or legally incapacitated or ineligible to provide informed consent
•Co-recruitment/participation in another clinical trial where there is a pharmaceutical or herbal or nutritional intervention (such trial interventions would also include: multi-vitamins, minerals, complementary and alternative medicines)
Preexisting inflammatory bowel disease (Ulcerative Colitis and Crohn’s disease)

Study & Design

• Study Type: Interventional
• Study Design: Not specified