NCT06114355尚未招募不适用
Comparison of Pre-operative EUS Guided and Intra-operative Direct Portal Vein Pressure Measurement in Pretransplant Cirrhotics - Prospective Observational Study
Asian Institute of Gastroenterology, India0 个研究点目标入组 25 人开始时间: 2023年12月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 25
- 主要终点
- Correlation between EUS-PPM with direct intra-operative portal pressure measurement (IO-PPM).
研究概览
简要总结
Direct portal pressure measurement under EUS-guidance (EUS-PPM) is a promising alternative to conventional indirect Hepatic Venous Pressure Gradient (HVPG). In patients undergoing liver transplantation for cirrhosis, high pre-operative portal vein (PV) pressure requires intra-operative portal vein inflow modulation (PIM). This pilot study aims to assess correlation between EUS-PPM with direct intra-operative portal pressure measurement (IO-PPM).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Liver cirrhosis patients scheduled for liver transplant for the standard indications within next 24- 48 hours will be included.
排除标准
- •Severe ascites not amenable for tapping
- •History of blood thinner consumption within last 5 days
- •Active duodenal ulcerations
结局指标
主要结局
Correlation between EUS-PPM with direct intra-operative portal pressure measurement (IO-PPM).
时间窗: 1 year
Correlation between EUS-PPM with direct intra-operative portal pressure measurement (IO-PPM).
次要结局
- Correlation between readings of EUS-PPM using portable manometry set and arterial transducer.(1 year)
研究者
Mohan Ramchandani
Consultant
Asian Institute of Gastroenterology, India
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