REtrospective Study of TESTIcular CAncer Patients at the University Magdeburg

Completed

• Conditions: Testicular Cancer

• Registration Number: NCT02092740
• Lead Sponsor: University of Magdeburg

Brief Summary

Retrospective analysis of treatment outcome and side effects of testicular cancer patients that had been diagnosed at the University Magdeburg from 1960 until 2012.

Detailed Description

Creating an ACCESS Windows form based Data Registry for testicular cancer patients.

Relevant data for testicular cancer patients based on EAU-guidelines 2013 and EORTC/RTOG, Lent-SOMA, CTC. All testicular cancer patients who had been histopathologically diagnosed al the Institute of Pathology at the University Magdeburg. About 2000 patients from 1960 until 2012. Postgraduate students collecting data requesting hospital documents, cancer registry of Sachsen-Anhalt, family practitioners and urologists as well as patients. Statistically Analysis with ACCESS and IBM SPSS statistics.

Study Timeline

• Study Start: 2012-11
• Primary Completion: 2012-12
• Study Completion: 2012-12
• Status Verified: 2014-03
• Study First Submitted: 2014-03-14
• Study First Submitted QC: 2014-03-18
• Study First Posted: 2014-03-20
• Last Update Submitted: 2014-03-20
• Last Update Posted: 2014-03-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 2000

Inclusion Criteria

• testicular cancer histopathologically diagnosed at the University Magdeburg Germany

Exclusion Criteria

• none.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Overall survival (OS)	Up to 52 years.	Overall survival (OS).

Secondary Outcome Measures

Name	Time	Method
Disease-specific survival.	Up to 52 years.	Disease-specific survival of testicular cancer.
Chronic side effects of testicular-cancer-specific radiation therapies.	Up to 52 years.	All Therapy Associated side effects of radiation therapy using EORTC (European Organisation for Research and Treatment of Cancer) /RTOG- (Radiation Therapy Oncology Group) - RTOG/EORTC Late Radiation Morbidity Scoring Schema), LENT-SOMA-(Late Effects of Normal Tissues)-, CTCAE-(Common Terminology Criteria for Adverse Events V4)-Scores. See
Chronic side effects of testicular-cancer-specific surgical therapies.	Up to 52 years.	All Therapy Associated side effects of surgical therapy using CTCAE-(Common Terminology Criteria for Adverse Events V4)-Score.
Secondary Malignoma	Up to 52 years.	Assessment of Development of Secondary malignoma after diagnosis of testicular cancer; Secondary malignoma other than testicular cancer and metachronous Primary testicular cancer
Chronic side effects of testicular-cancer-specific chemotherapies.	Up to 52 years.	All Therapy Associated side effects of chemotherapy using CTCAE-(Common Terminology Criteria for Adverse Events V4)-Score.
Cause of death.	Up to 52 years.	Cause of death.
Progressive-free survival (PFS).	Up to 52 years.	Progressive-free survival (PFS).
Relapse-free survival (RLS).	Up to 52 years.	Relapse-free survival (RLS).
Quality of Life (QoL).	Current situation.	Assessment of the current QoL using ECOG and EORTC-QLQ-C30-V3D.

Trial Locations

Locations (1)

Urology University Magdeburg; 🇩🇪 Magdeburg, Sachsen-Anhalt, Germany