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临床试验/NCT07711522
NCT07711522尚未招募1 期

The Efficacy of Quadro-Iliac Plane Block for Postoperative Analgesia in Patients Undergoing Posterior Spinal Instrumentation Surgery: A Randomized Prospective Controlled Trial

Istanbul Medipol University Hospital1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2026年8月1日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
1 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
The effect of ultrasound-guided quadro-iliac plane block (QIPB) on postoperative opioid consumption f

研究概览

简要总结

Posterior spinal instrumentation can cause significant postoperative pain due to extensive muscle dissection, manipulation of bone tissue, and implant placement. Providing optimal analgesia in the postoperative period is important for patients' functional recovery and early mobilization. Inadequate control of postoperative pain may delay recovery, increase the risk of opioid dependence, and lead to respiratory complications.

Although opioid analgesics are effective in reducing pain during the postoperative period, they are associated with side effects such as nausea, vomiting, respiratory depression, and the risk of dependence. Therefore, the use of non-opioid analgesic approaches is important for patient safety and comfort. For these reasons, regional analgesia techniques such as the modified thoracolumbar interfascial plane (TLIP) block and the erector spinae plane (ESP) block have recently become increasingly popular for postoperative pain control. The quadro-iliac plane block is a novel technique that targets the attachment area of the posterior surface of the quadratus lumborum muscle on the inner surface of the iliac crest. In this block, the spread of local anesthetic along the fascial planes surrounding the quadratus lumborum muscle may provide an anatomical mechanism contributing to analgesia of the lumbosacral, paraspinal, lower abdominal, and gluteal regions. However, as the quadro-iliac plane block is a new technique, there are not yet sufficient studies on this topic in the literature.

The primary objective of our study is to evaluate the effect of ultrasound-guided quadro-iliac plane block (QIPB) on postoperative opioid consumption after posterior spinal instrumentation. The secondary objectives are to compare opioid-related side effects, such as nausea, vomiting, and respiratory depression, as well as postoperative NRS (Numeric Rating Scale) pain scores between the groups.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Posterior spinal instrumentation patients

排除标准

  • Contraindications for regional analgesia
  • Allergies for local anesthetics

研究组 & 干预措施

Quadro-iliac block group

Active Comparator

干预措施: Paracetamol (acetaminophen) (Drug)

Quadro-iliac block group

Active Comparator

干预措施: Meperidine (Drug)

Wound infiltration Group

Other

干预措施: Meperidine (Drug)

Wound infiltration Group

Other

干预措施: Fentanyl (IV) (Drug)

Wound infiltration Group

Other

干预措施: Paracetamol (acetaminophen) (Drug)

Quadro-iliac block group

Active Comparator

干预措施: Fentanyl (IV) (Drug)

结局指标

主要结局

The effect of ultrasound-guided quadro-iliac plane block (QIPB) on postoperative opioid consumption f

时间窗: Postoperative 24 hours

The primary objective of this study is to evaluate the effect of ultrasound-guided quadro-iliac plane block (QIPB) on postoperative opioid consumption following posterior spinal instrumentation surgery.

次要结局

  • NRS of patients(Postoperative 24 hours)
  • Opioid related adverse effects(Postoperative 24 hours)

研究者

发起方
Istanbul Medipol University Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Fatma Pınar Uçar

M.D.

Istanbul Medipol University Hospital

研究点 (1)

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