Comparative evaluation of inflammatory biomarkers in peri implant crevicular fluid and crestal bone loss in two different implant collar designs at different time intervals:A clinical study
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 26
- 试验地点
- 1
- 主要终点
- 1. To evaluate the effect of Micro-Thread Collar Design on crestal bone levels and inflammatory biomarkers
研究概览
简要总结
New developments in implant design and surface technology have emerged to minimize crestal bone level changes. Since implant collar or crest module is a trans-osteal portion of the implant that plays an important role in peri implant tissue’s health condition, so assessment of biomarker in Peri Implant Crevicular Fluid (PICF) is a valuable diagnostic tool to maintain peri-implant health around crest module. Although few studies are available but there is a lack of consensus regarding superior retention of crestal bone levels by roughened collars when compared to smooth (machined) collars in human studies. There is also paucity of literature on the correlation of loss of crestal bone levels with inflammatory markers with relation to different collar designs. This study, therefore aims to compare the affect of collar design on crestal bone levels and inflammatory bio markers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with one missing tooth in the posterior mandibular molar area Patients with good oral hygiene Patients with adequate bone height and width to accommodate implant of appropriate dimension Co-operative patient, willing to give consent.
排除标准
- •Patients with a known history of any systemic diseases Patients with a history of smoking Patients with a history of intake of immunosuppressive drugs, anticoagulants, and anti-cancer drugs three months prior to the study Patients with a history of radiotherapy Pregnant and lactating women.
结局指标
主要结局
1. To evaluate the effect of Micro-Thread Collar Design on crestal bone levels and inflammatory biomarkers
时间窗: At the time of implant placement, 3 months and 6 months post-implant placement.
2. To evaluate the effect of Smooth Collar Design on crestal bone levels and inflammatory biomarkers
时间窗: At the time of implant placement, 3 months and 6 months post-implant placement.
次要结局
未报告次要终点
研究者
DrPaulina
Manav Rachna Dental College