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Clinical Trials/IRCT20190412043247N2
IRCT20190412043247N2
Not Yet Recruiting
Phase 4

The assessment of Empagliflozin Effects in diabetic patients with coronary artery disease: The EMPA-CARD Randomized Clinical Trial

Zanjan University of Medical Sciences0 sites100 target enrollmentTBD

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Not specified
Sponsor
Zanjan University of Medical Sciences
Enrollment
100
Status
Not Yet Recruiting
Last Updated
5 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
5 years ago
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Age between 40\-75 year\-old
  • HbA1c between 6\.5 to 9
  • Diabetes mellitus type 2
  • Under fix continues anti\-diabetic treatment for at least 3 month
  • BMI less than 40
  • Fixed Diet and physical activity
  • Resting heart rate between 60 to 100 b/min
  • Use of Aspirin 80 mg/Daily for at least 3 month prior to the beginning of study
  • Glomerular filtration rate (GFR)\>45
  • Documented known Coronary Artery Disease

Exclusion Criteria

  • Heart Failure (NYHA class 3\-4\), Ejection Fraction \<40%
  • History of allergic reaction to SGLT2 inhibitors Drugs
  • History of SGLT2 inhibitor Drugs usage
  • Gastrointestinal malabsorbtion disease
  • History of CABG, ACS, TIA,CVA or PCI during past 3 month
  • History or presence of malignancy
  • Anemia (Hb\<10 g/dl)
  • History of heart or lung transplant
  • Major psychiatric disorders
  • History of DKA

Outcomes

Primary Outcomes

Not specified

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