Chemical Shift Encoding-based Water-fat Magnetic Resonance Imaging in Spinal Tumors

• Conditions: Bone Tumor; Spinal Tumor
• Interventions: Diagnostic Test: Chemical shift encoding-based water-fat MRI

• Registration Number: NCT05631002
• Lead Sponsor: Peking University Third Hospital

Brief Summary

Fat composition of the spinal tumors is positively correlated with classification and differential diagnosis of benign and malignant tumors.

Detailed Description

Chemical shift encoding-based water-fat magnetic resonance imaging (MRI) is a non-invasive method that provides quantitative information about the biochemical water-fat composition of bone marrow and skeletal muscle in vivo.

Study Timeline

• Status Verified: 2022-08
• Study Start: 2022-08-01
• Study First Submitted: 2022-11-20
• Study First Submitted QC: 2022-11-20
• Last Update Submitted: 2022-11-20
• Study First Posted: 2022-11-30
• Last Update Posted: 2022-11-30
• Primary Completion: 2023-12-01
• Study Completion: 2023-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• Pathological biopsy of a patient with diagnosed spinal tumor lesion, and preoperative examination Chemical shift encoding-based water-fat MRI was performed.

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Exclusion Criteria

• Recurrent neoplasms; Lesion diameter < 1 cm; Poor image quality.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients with benign spinal tumor	Chemical shift encoding-based water-fat MRI	-
Patients with intermediate spinal tumor	Chemical shift encoding-based water-fat MRI	-
Patients with malignant spinal tumor	Chemical shift encoding-based water-fat MRI	-

Primary Outcome Measures

Name	Time	Method
Type of tumor	One month before treatment	Pathological diagnosis

Trial Locations

Locations (1)

Peking University third hospital; 🇨🇳 Beijing, Beijing, China