Factors Associated With the Prognosis of Patients Admitted to for Acute Obstructive Pyelonephritis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 575
- 试验地点
- 1
- 主要终点
- The primary endpoint will be a combined endpoint of death, and/or stage 3 AKI ( KDIGO classification), and/or non-recovery of renal function.
研究概览
简要总结
Acute obstructive pyelonephritis is a condition with a high risk of complications and may require admission to the intensive care unit.
Most of the available data on this condition comes from small, retrospective, single-centre series.
To date, no large-scale study has examined the factors associated with the prognosis of patients admitted to intensive care for acute obstructive pyelonephritis.
The aim of this study is to describe the population and prognosis of patients admitted to the intensive care unit for the management of acute obstructive pyelonephritis, and to identify factors associated with a poor prognosis in these patients.
详细描述
The retrospective and multicenter study consists of a retrospective and pseudonymous collection of data from medical reports of patients treated, over the period 2015-2022, in each intensive care unit agreeing to participate, .
Investigators from each participating center will be responsible for screening on all hospitalized patients over the period 2015-2022. Patients who have been hospitalized for the management of acute obstructive pyelonephritis will be included, in the absence of non-inclusion criteria.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients over 18 years of age
- •Hospitalized in intensive care for management of acute obstructive pyelonephritis
- •Patients affiliated to a Social Security System
排除标准
- •Pregnancy
- •Opposition to data use
- •Persons under legal protection (curatorship, guardianship), legal safeguards
结局指标
主要结局
The primary endpoint will be a combined endpoint of death, and/or stage 3 AKI ( KDIGO classification), and/or non-recovery of renal function.
时间窗: up to 30 days after admission to intensive care
次要结局
- the incidence of acute renal failure defined by KDIGO 2 and 3(up to 30 days after admission to intensive care)
- the incidence of Renal replacement therapy(up to 30 days after admission to intensive care)
- The number of days alive without Renal replacement therapy(up to 30 days after admission to intensive care)
- the incidence of non-recovery of renal fuction(up to 30 days after admission to intensive care)
- The number of days alive without antibiotics(up to 30 days after admission to intensive care)
- Death(up to 30 days after admission to intensive care)
- Stage 3 Acute kidney injury (KDIGO classification)(up to 30 days after admission to intensive care)
- failure to recover renal function(up to 30 days after admission to intensive care .)
- the incidence of acute renal failure defined by KDIGO 1(up to 30 days after admission to intensive care)
- The number of days alive without catecholamines(up to 30 days after admission to intensive care)
- The number of days alive without(up to 30 days after admission to intensive care)
- Death rate(up to 30 days after admission to intensive care)