Comparative Evaluation Of Salivary Anaerobic Microbial Count In Plaque Induced Gingivitis In Subjects Using Virgin Coconut Oil Pulling And Chlorhexidine Mouthwash
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Reduction in salivary anaerobic microbial count in both subjects using chlorhexidine mouthwash and coconut oil pulling
研究概览
简要总结
•A total of 30 subjects with chronic plaque -induced mild to moderate gingivitis in the age group 18 to 30 years will be recruited and they will be divided into group A and Group B each with 15 subjects.
•Group A subjects will be advised to perform virgin coconut oil pulling (The Happy Grove Virgin Coconut Oil, KCK Agroproducts ) and group B will be advised to use Chlorhexidine Gluconate 0.12% solution (Periogard Mouthwash, Colgate Palmolive) for 15 days as an adjunct to routine tooth brushing.
•Subjects will be recalled after 15 days and oral prophylaxis will be performed and shall be instructed to discontinue mouthwash and oil pulling.
•Gingival and Plaque indices will be estimated at the three visits (baseline,15 days, and 30 days). Salivary anaerobic microbial counts also shall be estimated for both the study groups using RT-PCR during the three visits.
RESULTS
Based on statistical results using t test coconut oil pulling and chlorhexidine mouthwash have comparable effects on gingival status. So, we conclude that oil pulling using coconut oil is an effective adjuvant oral hygiene practice in reducing severity of mild to moderate plaque induced gingivitis along with routine oral hygiene measures. Coconut oil pulling could be a potential alternative to chlorhexidine mouthwash for long term use.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 30.00 Year(s)（—）
- 性别
- All
入选标准
- •Systemically healthy individuals within the age group 18 – 30 years diagnosed with chronic gingivitis Subjects willing to participate in the study.
排除标准
- •History of oral prophylaxis within six months prior to the start of the study.
- •The use of antibiotics or mouthwashes within three months prior to the start of the study.
- •Use of tobacco Ongoing fixed orthodontic therapy.
结局指标
主要结局
Reduction in salivary anaerobic microbial count in both subjects using chlorhexidine mouthwash and coconut oil pulling
时间窗: Time points : 1 month
次要结局
- Improvement in the gingival status of both subjects using chlorhexidine mouthwash & coconut oil pulling(1 month)
研究者
DR Lakshmi K R
Mar Baselios Dental College