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临床试验/NCT01470430
NCT01470430撤回不适用

Study to Measure Systemic VEGF Levels in ROP Infants Following Intravitreal Anti-VEGF Therapy or Retinal Laser Treatment

University Hospital Freiburg1 个研究点 分布在 1 个国家开始时间: 2012年3月最近更新:
适应症

试验速览

阶段
不适用
状态
撤回
发起方
试验地点
1
主要终点
Systemic VEGF levels following treatment

研究概览

简要总结

The purpose of this study is to measure systemic levels of vascular endothelial growth factor (VEGF) and other proteins (e.g. IGF-1) in the systemic circulation of infants with retinopathy of prematurity (ROP) following ocular treatment with either intravitreal injections of anti-VEGF agents or retinal laser photocoagulation. The primary aim is to determine if serum VEGF levels change after treatment.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Clinical diagnosis of retinopathy of prematurity requiring treatment

排除标准

  • 未提供

结局指标

主要结局

Systemic VEGF levels following treatment

时间窗: 16 weeks

comparing VEGF levels in serum of ROP infants treated with intravitreal anti-VEGF agents vs. retinal laser photocoagulation over 16 weeks post treatment

次要结局

  • Systemic levels of other growth factors (e.g. IGF-1)(16 weeks)

研究者

发起方
University Hospital Freiburg
申办方类型
Other
责任方
Principal Investigator
主要研究者

Andreas Stahl, MD

MD

University Hospital Freiburg

研究点 (1)

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