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Clinical Trials/NCT05648721
NCT05648721
Recruiting
Not Applicable

The Effects of a Digital Application for Gestational Diabetes Management in Improving Patients' Compliance and Satisfaction, Glycemic Control and Pregnancy Outcomes: A Multicenter Randomized Controlled Trial

The Baruch Padeh Medical Center, Poriya5 sites in 1 country110 target enrollmentMay 18, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Gestational Diabetes
Sponsor
The Baruch Padeh Medical Center, Poriya
Enrollment
110
Locations
5
Primary Endpoint
Patient compliance
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

Gestational diabetes mellitus (GDM) is the most prevalent complication in pregnancy. Patients' follow-up and treatment is performed in specialized GDM clinics that teach and support women in implementing lifestyle changes, blood glucose self-monitoring, and nutritional and pharmacologic therapy.

Recently, mobile health (mHealth) applications have been introduced as a resource to improve self-management and follow-up among pregnant women. The proposed study will examine the efficacy of the GDM management mHealth application in improving patients' compliance and satisfaction, glycemic control, and pregnancy outcomes.

A multicenter randomized controlled trial of women with GDM treated in the GDM clinics. Women will be randomly allocated to a research group that will use the GDM application and a control group that will receive regular follow-up without the GDM application. The primary outcome is patient compliance, defined as the actual blood glucose measurements/instructed measurements ×100. Secondary outcomes include glycemic control parameters, and maternal and neonatal complications.

Registry
clinicaltrials.gov
Start Date
May 18, 2023
End Date
April 2026
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Pregnant women diagnosed with GDM from 13.0 gestational week
  • Recruitment until 34.0 gestational week
  • 18 years old and older
  • Singleton pregnancy

Exclusion Criteria

  • Women with pre-gestational diabetes mellitus
  • Multiple pregnancy
  • Women without a Smartphone that can support the GDM application
  • Refusal to participate

Outcomes

Primary Outcomes

Patient compliance

Time Frame: During the follow up in the clinic (around 4 months)

Defined as the actual blood glucose measurements/instructed measurements ×100

Secondary Outcomes

  • Neonatal death(During hospitalization after delivery (around the first week))
  • Apgar score(One and Five minutes after birth)
  • Neonatal birth weight(At birth)
  • Number of neonates who needed phototherapy(During hospitalization after delivery (around the first week))
  • Percentage of off-target glucose measurements(During the follow up in the clinic (around 4 months))
  • Instrumental or cesarean delivery(At birth)
  • shoulder dystocia(At birth)
  • Patients' satisfaction from the monitoring protocol(Will be evaluated up to 2 months after birth)
  • Mean blood glucose of the daily glucose charts(During the follow up in the clinic (around 4 months))
  • Preeclampsia/gestational hypertension(During the follow up in the clinic (around 4 months))
  • Respiratory morbidity of the newborn(During hospitalization after delivery (around one week))
  • polyhydramnios(During the follow up in the clinic (around 4 months))
  • Hypoglycemia of the newborn(During hospitalization after delivery (around one week))
  • Induction of labor(At birth)
  • Neonatal intensive care unit admission(A week after delivery)
  • Neonatal hypocalcemia(During hospitalization after delivery (around the first week))
  • Neonatal hypomagnesemia(During hospitalization after delivery (around the first week))
  • Need for pharmacotherapy for glycemic control(During the follow up in the clinic (around 4 months))
  • Third- or fourth-degree perineal tears(At birth)

Study Sites (5)

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