Comparison between erector spinae plane block versus serratus anterior plane block regarding analgesia and stress response after modified radical mastectomy.

helwan university0 sites60 target enrollmentSeptember 6, 2023

Overview

No summary available.

Registry

who.int

Start Date

September 6, 2023

End Date

TBD

Last Updated

2 years ago

Study Type

Interventional

Sex

Female

Sponsor

•Female patients
•Type of surgery; Modified Radical Mastectomy MRM
•Physical status: ASA I and ASA II.
•Age \= 35 and \= 60 Years in order to standardize doses of anesthetics and decrease age group difference in responses.
•Body mass index (BMI): \= 20 kg/m2 and \= 35 kg/m2\.

•Patient refusal
•Known sensitivity or contraindication to drugs used in the study (local anesthetics, opioids). History of psychological disorders and/or chronic pain syndrome.
•Contraindication to regional anesthesia e.g. local sepsis, pre\-existing peripheral neuropathies, coagulopathy and clinical skin infiltration by the tumor.
•Severe respiratory e.g. (sever obstructive pulmonary disease (forced expiratory volume /forced vital capacity FEV1/FVC \<50% or sever restrictive pulmonary disease (total lung capacity TLC\<40%), adult respiratory distress syndrome) or sever cardiac disorders e.g. (heart failure). (Martinez\-Pitre, Sabbula and Cascella, 2021\)
•Advanced liver disease (Elevated liver enzymes more than 3 folds of normal range).
•Advanced kidney disease (Decreased creatinine clearance \<40 ml/min). (Stevens et al., 2006\)