Evaluating the effect of Donepezil on Cerebral Blood Flow Velocity in Alzheimer's disease

Not Applicable

• Conditions: Condition 1: Alzheimer's disease. Condition 2: Alzheimer's disease.; Dementia in Alzheimer's disease; Alzheimer's disease

• Registration Number: IRCT138812183518N1
• Lead Sponsor: Isfahan University of Medical Sciences, Isfahan, Iran

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

The inclusion criteria : age between 50 and 80 years, and the exclusion criteria : history of stroke, nontreated hypertension, diabetes mellitus, smoking during the past 10 years, hypercholesterolemia and taking AchEI drugs one month prior to the study.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mini Mental State Examination. Timepoint: before, 1 month and 2 months after intervention. Method of measurement: with checklist.;Peak systolic flow velocity. Timepoint: before, 1 month and 2 months after intervention. Method of measurement: Transcranial Doppler sonography.;Peak diastolic flow velocity. Timepoint: before, 1 month and 2 months after intervention. Method of measurement: Transcranial Doppler sonography.;Mean flow velocity. Timepoint: before, 1 month and 2 months after intervention. Method of measurement: Transcranial Doppler sonography.