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Study of 0416 Ointment in the Treatment of Atopic Dermatitis

Phase 3
Completed
Conditions
Atopic Dermatitis
Interventions
Drug: 0416
Drug: Vehicle of 0416 test product
Registration Number
NCT01053247
Lead Sponsor
Fougera Pharmaceuticals Inc.
Brief Summary

The aim of this trial is to assess the efficacy of 0416 Ointment in the Treatment of Atopic Dermatitis.

Treatment medication will be administered as follows: Apply a thin layer of ointment to affected skin areas twice daily and rub in gently and completely. Study medication will be applied twice a day, approximately 12 hours apart, for approximately 2 weeks.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
793
Inclusion Criteria
  • Clinical diagnosis of Atopic Dermatitis
  • Good health with the exception of Atopic Dermatitis
  • Percent Body Surface Area minimum requirements
Exclusion Criteria
  • Subjects who are pregnant, nursing, or planning a pregnancy within the study participation period.
  • Subjects who have any systemic or dermatological disorders with the exception of Atopic Dermatitis

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Test0416Test product that contains the active pharmaceutical ingredient
Referencetacrolimus ointment 0.1%Reference product that contains active pharmaceutical ingredient
VehicleVehicle of 0416 test productPlacebo that contains no active pharmaceutical ingredient
Primary Outcome Measures
NameTimeMethod
Incidence of Success Based on the Investigator's Global Evaluation at the End of Treatment2 weeks
Secondary Outcome Measures
NameTimeMethod
The Mean Change From Baseline in the Total Individual Clinical Signs and Symptoms Per Body Region, the Mean Change From Baseline in Pruritus and Mean Change From Baseline in the Percentage Total Body Surface Affected (%BSA).2 weeks

Trial Locations

Locations (1)

Fougera Pharmaceuticals Inc.

🇺🇸

Melville, New York, United States

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