Research on Key Techniques for Intelligent Diagnosis and Ablation Decision-making of Liver Cancer and Evolution by Contrast-enhanced Ultrasound
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 5,000
- 试验地点
- 1
- 主要终点
- specificity
研究概览
简要总结
Contrast-enhanced ultrasound (CEUS) substantially improves the potential of ultrasound (US) for the identification and characterization of focal liver lesions (FLLs). Compared to contrasted-enhanced MRI and CT, it has some unique advantages, such as the absence of ionizing radiation, and easy operability and repeatability. However, the efficacy of CEUS in diagnosing liver lesions is challenged by several factors including being highly dependent on doctor's experience, low signal-to-noise ratio, and low interobserver agreement. Therefore, it is a beneficial attempt to construct an intelligent CEUS diagnosis system using digital information technology. This study aims to collect standard data of CEUS cines recordings and develop deep learning model for accurate segmentation, detection and classification of liver lesions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with a solid liver tumor visible during routine ultrasound and received CEUS.
- •disease history and standard of reference of the lesions can be acquired
排除标准
- •hypersensitivity for ultrasound contrast media
- •pregnant or lactating patients
- •previously treated lesions or local relapse from previously treated lesions
- •diffuse tumors
结局指标
主要结局
specificity
时间窗: through study completion, an average of 7 year
diagnosis specificity of intelligent CEUS analysis
AUC value
时间窗: through study completion, an average of 7 year
Area under the receiver operating characteristic (ROC) curve (AUC)
sensitivity
时间窗: through study completion, an average of 3 year
diagnosis sensitivity of intelligent ultrasound analysis
次要结局
未报告次要终点
研究者
Ping Liang
Prof
Chinese PLA General Hospital
