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临床试验/NCT04682886
NCT04682886招募中不适用

Research on Key Techniques for Intelligent Diagnosis and Ablation Decision-making of Liver Cancer and Evolution by Contrast-enhanced Ultrasound

Ping Liang1 个研究点 分布在 1 个国家目标入组 5,000 人开始时间: 2017年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
5,000
试验地点
1
主要终点
specificity

研究概览

简要总结

Contrast-enhanced ultrasound (CEUS) substantially improves the potential of ultrasound (US) for the identification and characterization of focal liver lesions (FLLs). Compared to contrasted-enhanced MRI and CT, it has some unique advantages, such as the absence of ionizing radiation, and easy operability and repeatability. However, the efficacy of CEUS in diagnosing liver lesions is challenged by several factors including being highly dependent on doctor's experience, low signal-to-noise ratio, and low interobserver agreement. Therefore, it is a beneficial attempt to construct an intelligent CEUS diagnosis system using digital information technology. This study aims to collect standard data of CEUS cines recordings and develop deep learning model for accurate segmentation, detection and classification of liver lesions.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • patients with a solid liver tumor visible during routine ultrasound and received CEUS.
  • disease history and standard of reference of the lesions can be acquired

排除标准

  • hypersensitivity for ultrasound contrast media
  • pregnant or lactating patients
  • previously treated lesions or local relapse from previously treated lesions
  • diffuse tumors

结局指标

主要结局

specificity

时间窗: through study completion, an average of 7 year

diagnosis specificity of intelligent CEUS analysis

AUC value

时间窗: through study completion, an average of 7 year

Area under the receiver operating characteristic (ROC) curve (AUC)

sensitivity

时间窗: through study completion, an average of 3 year

diagnosis sensitivity of intelligent ultrasound analysis

次要结局

未报告次要终点

研究者

发起方
Ping Liang
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Ping Liang

Prof

Chinese PLA General Hospital

研究点 (1)

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