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Clinical Trials/CTRI/2020/06/025646
CTRI/2020/06/025646
Not yet recruiting
Phase 4

Evaluation of effect of Mandibular Advancement Device on Inflammatory marker (TNF-alpha) in patients with Obstructive Sleep Apnoea: A controlled before and after study

Office of the Research Cell0 sites0 target enrollmentTBD
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ConditionsHealth Condition 1: G473- Sleep apnea

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Health Condition 1: G473- Sleep apnea
Sponsor
Office of the Research Cell
Status
Not yet recruiting
Last Updated
4 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional

Investigators

Sponsor
Office of the Research Cell

Eligibility Criteria

Inclusion Criteria

  • •1\. Subjects in the age group of 25\-65 years.
  • •2\. Ability to understand the procedure and provide informed consent before being included in the study.
  • •3\. Patients with mild to moderate Obstructive Sleep Apnoea.
  • •4\. Patients with no previous OSA treatment history.
  • •5\. \>8 stable natural teeth per jaw with no periodontal condition like periodontitis etc.

Exclusion Criteria

  • •1\. Current smoking habit with moderate to heavy smoking (more than 10 cigarettes per day).
  • •2\. History of infectious diseases, rheumatic diseases, immunological diseases, tumours, peripheral vascular diseases, coagulation disorders, severe psychogenic disorders, or acute or chronic kidney failure.
  • •3\. History of injury or surgery in past three months.
  • •4\. Administration of drugs (anti\-inflammatory, TNF\- α blockers), hormones, immune suppressors, cytotoxins, free radical scavengers.
  • •5\. OSA patients already receiving/received treatment.

Outcomes

Primary Outcomes

Not specified

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