Evaluation of effect of Mandibular Advancement Device on Inflammatory marker (TNF-alpha) in patients with Obstructive Sleep Apnoea: A controlled before and after study

Office of the Research Cell0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•1. Subjects in the age group of 25-65 years.
•2. Ability to understand the procedure and provide informed consent before being included in the study.
•3. Patients with mild to moderate Obstructive Sleep Apnoea.
•4. Patients with no previous OSA treatment history.
•5. >8 stable natural teeth per jaw with no periodontal condition like periodontitis etc.

•1. Current smoking habit with moderate to heavy smoking (more than 10 cigarettes per day).
•2. History of infectious diseases, rheumatic diseases, immunological diseases, tumours, peripheral vascular diseases, coagulation disorders, severe psychogenic disorders, or acute or chronic kidney failure.
•3. History of injury or surgery in past three months.
•4. Administration of drugs (anti-inflammatory, TNF- Î± blockers), hormones, immune suppressors, cytotoxins, free radical scavengers.
•5. OSA patients already receiving/received treatment.

发起方

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