A RANDOMIZED CONTROLLED CLINICAL TRIAL ON APPLICATION OF JYOTISMATI GEL IN THE MANAGEMENT OF PARIKARTIKA FISSURE IN ANO
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
研究概览
简要总结
Fissure in Ano is a common anorectal condition presenting with pain and burning sensation and can be correlated with Parikartika described in Ayurveda. The prevalence of anal fissure is high in India, especially in Tamil Nadu, largely due to unhealthy dietary habits. Conventional management includes conservative and surgical methods; however, surgical procedures may be associated with complications, emphasizing the need for a safe, cost-effective, and patient-friendly treatment.
Parikartika is a Vatapitta-dominant condition localized to the Guda and is characterized by pain, burning sensation, bleeding, and constipation. Ayurvedic conservative management has shown good efficacy in such conditions.
Jyotismati (Celastrus paniculata) possesses analgesic, anti-inflammatory, wound-healing, and antibacterial properties, while jatyadi ghrutam is a classical formulation indicated in wound management and anorectal disorders.
This randomized controlled clinical study aims to evaluate and compare the efficacy of jyotismati gel and jatyadi ghrutam in the management of Parikartika (Fissure in Ano). Dietary modifications and lifestyle advice will be provided to all participants. The study will assess improvement in pain, burning sensation, bleeding, fissure healing, and overall patient com
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Subject diagnosed with Fissure-in-Ano as per the above diagnostic criteria.
- •Subject between the age group of 18-60 years.
排除标准
- •Subjects diagnosed with cases of Crohn’s disease, Diverticulitis, and Ulcerative colitis
- •Severe anal stenosis
- •Congenital anomalies of rectum and anal canal
- •Subjects diagnosed with malignancy
- •Known case of HIV, Syphilis, TB.
- •Localized infection.
- •Pregnant Women.
研究者
Ganesh V
Sri Jayendra Saraswathi Ayurveda College and Hospital