Tear Collection in Adult Volunteers

Completed

• Conditions: Healthy Volunteers

• Registration Number: NCT01969162
• Lead Sponsor: Allergan

Brief Summary

This exploratory study will collect tear samples from adult volunteers for determining and quantifying tear composition profiles. No investigational drug will be administered in this study.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-09
• Study First Submitted: 2013-10-21
• Study First Submitted QC: 2013-10-23
• Study First Posted: 2013-10-25
• Primary Completion: 2013-11
• Study Completion: 2013-11
• Status Verified: 2014-11
• Results First Submitted: 2014-11-17
• Results First Submitted QC: 2014-11-17
• Last Update Submitted: 2014-11-17
• Results First Posted: 2014-11-21
• Last Update Posted: 2014-11-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

-Adult volunteers without ocular disease.

Exclusion Criteria

• Systemic medications that could affect eye health taken within 1 month of enrollment
• Eye infection or inflammation in either eye 3 months prior to screening
• History of herpes in either eye
• Diagnosis of dry eye or meibomian gland dysfunction
• Diagnosis of glaucoma
• Allergic conjunctivitis
• Use of rigid contact lenses within 1 year of screening
• Use of soft contact lenses within 1 week of enrollment.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Tear Lipid Composition Profile	Day 1	Basal (non-stimulated) tear samples were collected from one eye for lipid analysis. 13 different lipids classes were detected in individual tear samples. The concentration of each lipid class is reported in picomoles (pmole).