Efficacy Of Topical Terbinafine And Sertaconazole In Combination With Oral Itraconazole In Treatment Of Dermatophytosis
Not Applicable
Completed
- Conditions
- Health Condition 1: L088- Other specified local infections of the skin and subcutaneous tissue
- Registration Number
- CTRI/2020/08/027328
- Lead Sponsor
- Armed Forces Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Adults between the age of 18-65 years, clinically diagnosed as tinea corporis and tinea cruris and confirmed by positive KOH mount microscopy
Exclusion Criteria
Anyone who has taken systemic or topical antifungals in the four weeks prior to initiation of study; or presents with solitary lesion, history of hypersensitivity to antifungals, on any systemic medications known to have interactions with itraconazole, or with superadded bacterial infections, pregnancy or lactating and on immunosuppressive drugs or with any immunosuppressive disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complete cure: Clearance on microscopy, no residual signs & symptoms (Except Post inflammatory hyperpigmentation) <br/ ><br>Mild resolution: Upto 25% improvement <br/ ><br>Moderate resolution: 25-50% improvement <br/ ><br>Significant resolution: 51-99% improvementTimepoint: 0, 2 and 4 weeks
- Secondary Outcome Measures
Name Time Method Side effects due to the medicationsTimepoint: 0, 2 and 4 weeks;Time of clinical cure and improvementTimepoint: 0, 2 and 4 weeks