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the effect of an herbal Formula of Zizifus Jujuba on elderly functional constipatio

Phase 3
Recruiting
Conditions
Functional constipation of the elderly.
Registration Number
IRCT20231022059800N1
Lead Sponsor
Mazandaran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
60
Inclusion Criteria

Age above 60 years, when the presence of functional constipation based on Roman IV indicators has been confirmed by a respected gastroenterologist.

Exclusion Criteria

History of allergy to jujube fruit or jujube product or pidrolox powder.
Use of anti-Parkinson drugs, anti-psychotics, tricyclic antidepressants, anti-convulsants, anti-cholinergics, anti-spasms, anti-neoplastic, calcium blockers, 5HT antagonists, iron products.Alcohol and drug abuse.
Suffering from severe mental illness and psychiatric disorders.
Suffering from neurological diseases such as multiple sclerosis, Parkinson's, progressive systemic sclerosis, spinal cord injury, stroke.
Suffering from a metabolic disease such as uncontrolled diabetes, hypothyroidism, hypercalcemia, pheochromocytoma, and any organic disease related to constipation, severe asthma, and bronchitis. Cardiac and hematological patients in case of taking drugs that cause constipation, including calcium blockers, furosemide, iron products, opioids.
Inability to do physical activity and having special medical conditions such as inability to move.
History of intestinal or stomach surgery, ostomy.
History of malignancy and cancer.
Kidney and liver failure.
Endoscopy, colonoscopy, and radiology report in the last 5 years that has any abnormality and malignancy or IBD.
Stool has abnormal OB, FBS, TFT, Ca.
Viral gastroenteritis symptoms in the last two weeks.

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
umber of bowel movements per week. Timepoint: Before the start of the intervention (beginning of the intervention) and days 28, 21, 14, after the intervention. Method of measurement: Asking the patient through a questionnaire.
Secondary Outcome Measures
NameTimeMethod
Feeling of incomplete emptying after defecation. Timepoint: Before the start of the intervention (beginning of the intervention) and days 28, 21, 14, after the intervention. Method of measurement: Questionnaire and questions from the patient.;Number of times of manual maneuver in defecation. Timepoint: Before the start of the intervention (beginning of the intervention) and days 28, 21, 14, after the intervention. Method of measurement: Questionnaire and questions from the patient.;Consistency of stool. Timepoint: Before the start of the intervention (beginning of the intervention) and days 28, 21, 14, after the intervention. Method of measurement: Questionnaire and questions from the patient.;The quality of life. Timepoint: Before the start of the intervention (beginning of the intervention) and days 28, 21, 14, after the intervention. Method of measurement: Quality of life questionnaire for functional constipation patients.
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