Internet Delivered Cognitive Behavior Therapy for Trichotillomania and Skin Picking Disorder

Karolinska Institutet1 site in 1 country25 target enrollmentOctober 5, 2020

ConditionsTrichotillomania Excoriation (Skin-Picking) Disorder

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Trichotillomania
Sponsor: Karolinska Institutet
Enrollment: 25
Locations: 1
Primary Endpoint: The Massachusetts General Hospital Hairpulling Scale
Status: Completed
Last Updated: 3 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The primary aim of the study is to test the feasibility, safety and efficacy of a manual based, Internet-delivered, behavior therapy (I-BT) for trichotillomania and skin picking disorder.

Registry

clinicaltrials.gov

Start Date

October 5, 2020

End Date

December 23, 2021

Last Updated

3 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Karolinska Institutet

Responsible Party

Principal Investigator

Volen Ivanov

Principal Investigator

Karolinska Institutet

Eligibility Criteria

Inclusion Criteria

•Primary diagnosis of trichotillomania and/or skin picking disorder according to DSM-5
•Living in Sweden with a Swedish personal identification number
•Able to participate in study assessment in Swedish and understand Swedish text
•Have regular access to a computer with Internet access and skills to use Internet
•Signed informed consent
•Outpatient

Exclusion Criteria

•Psychotropic medication changes that can affect symptoms of trichotillomania or skin picking disorder within 2 months prior to treatment
•Other ongoing psychological treatments that could affect symptoms of trichotillomania or skin picking disorder
•Completed CBT for trichotillomania or skin picking disorder within the last 24 months
•Ongoing substance dependence or misuse
•Lifetime bipolar disorder or psychosis
•Suicidal ideation (a score of 5 points or higher on item 9 on the self-reported Montgomery-Åsberg depression rating scale
•Psychiatric comorbidity that could severely jeopardize treatment participation

Outcomes

Primary Outcomes

The Massachusetts General Hospital Hairpulling Scale

Time Frame: Change from baseline (week 0) to post-treatment (week 10), 1-, 3-, 6- and 12-month follow-up.

A self-report instrument for assessing repetitive hairpulling. The scale consists of seven items, rated for severity from 0 to 4 which assess urges to pull, actual pulling, perceived control, and associated distress.

The Skin Picking Scale - Revised

Time Frame: Change from baseline (week 0) to post-treatment (week 10), 1-, 3-, 6- and 12-month follow-up.

A 6-item self-report measure of skin picking disorder severity.

Secondary Outcomes

Montgomery Åsberg Depression Rating Scale Self Rate(Change from baseline (week 0) to post-treatment (week 10), 1-, 3-, 6- and 12-month follow-up.)
Acceptance and Action Questionnaire(Change from baseline (week 0) to post-treatment (week 10), 1-, 3-, 6- and 12-month follow-up.)
The Skin Picking Impact Scale(Change from baseline (week 0) to post-treatment (week 10), 1-, 3-, 6- and 12-month follow-up.)
The NIMH Trichotillomania Symptom Severity Scale(Change from baseline (week 0) to post-treatment (week 10) and 12-month follow-up.)
The NIMH Trichotillomania a Impairment Scale(Change from baseline (week 0) to post-treatment (week 10) and 12-month follow-up.)
Treatment credibility scale.(Scores at mid-treatment (week 5) and post-treatment (week 10).)
Clinical global impression - severity scale.(Change from baseline (week 0) to post-treatment (week 10)] and 12-month follow-up.)
Negative events questionnaire (NEQ).(Ratings at post-treatment (week 10).)
Sheehan Disability Scale(Change from baseline (week 0) to post-treatment (week 10), 1-, 3-, 6- and 12-month follow-up.)
EuroQol 5D, (EQ5D).(Change from baseline (week 0) to post-treatment (week 10) and 12-month follow-up.)
Working Alliance Inventory - Short Form.(Scores at mid-treatment (week 5) and post-treatment (week 10).)
Global Assessment of functioning scale(Change from baseline (week 0) to post-treatment (week 10) and 12-month follow-up.)
Acceptance and Action Questionnaire for Trichotillomania(Change from baseline (week 0) to post-treatment (week 10), 1-, 3-, 6- and 12-month follow-up.)
Patient Health Questionnaire 9.(Change from baseline (week 0) to post-treatment (week 10) and 12-month follow-up.)
Client Satisfaction Questionnaire-8.(Scores at post-treatment (week 10).)
Clinical global impression - improvement scale.(Ratings at post-treatment (week 10) and at 12-month follow-up.)