NL-OMON37674
Completed
Not Applicable
Clinical evaluation of the underlying mechanisms of targeted therapy related toxicities - mechanisms of toxicity of targeted agents
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Skin and mucosal toxicities of targeted therapies
- Sponsor
- Vrije Universiteit Medisch Centrum
- Enrollment
- 120
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients that will start palliative treatment with TKIs, mTOR inhibitors, ipilimumab, vemurafenib or anti\-EGFR antibodies and therefore fulfill according to their attending physician all the usual criteria for receiving standard targeted therapy as monotherapy.
- •2\. PT\-INR/PTT \< 1\.5 x ULN.
- •3\. Platelet count \> 100 x 109/l
Exclusion Criteria
- •\* Concomitant use of anticoagulants
- •\* Previous colonic surgery in the last 3 months
- •\* History of inflammatory bowel disease, or other active gastrointestinal infection
Outcomes
Primary Outcomes
Not specified
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