Clinical evaluation of siddha formulation Seenthil chooranam (internal) and Vetitver thailam (external) in the management of Neer Peenisam (sinusitis) among out-patients attending Ayothidoss Pandithar hospital, National Institute of Siddha
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- The outcome will be mainly assessed by reduction in clinical symptoms after the
研究概览
简要总结
INTRODUCTION:
This is a clinical trial that evaluates the effectiveness of siddha formulation Seenthil chooranam ( internal) and Vetiver thailam (external) in the management of Neer peenisam (Sinusitis) in patients through Adelaide Disease Severity Score and clinical lab parameters–TC,DC, ESR, AEC and IgE pre and post treatment. Sinusitis is the inflammation of the sinuses, which are air filled cavities in the skull. The types of sinuses are maxillary, frontal, ethmoid and sphenoid. Among these maxillary and ethmoid sinuses quite often gets infected. The most frequently involved one is maxillary sinus. The overall prevalence of sinusitis was found to be 1.11%. The mean age of patients was 34 years and 70% of patients were suffering from chronic maxillary sinusitis. There is 20% of patients have positive family history of sinusitis.
PRIMARY OBJECTIVE:
To evaluate the clinical effectiveness of siddha formulations Seenthil chooranam (internal) and vetiver thailam (external) in the management of neer peenisam (sinusitis) by using Adelaide Disease Severity Score.
SECONDARY OBJECTIVE:
To observe changes in clinical lab parameters–TC,DC, ESR, AEC and IgE pre and post treatment.
MATERIALS AND METHODS:
A total of 30 diagnosed adult patients of Neer peenisam willing to participate in the study , by signing the consent form will be enrolled in the study . Having Headache / sneezing/nasal congestion/ rhinorrhea/ postnasaldrip/ facial pain/ anosmia, Pain and tenderness over paranasal sinuses, Patient who has Adelaide Disease Severity Score above 12 will be included in this study and who are known case of migrane,tumours in PNS X-ray, Pregnancy and lactating mother, Patients with uncontrolled Diabetes mellitus are excluded. Assesssment will be done through Adelaide Disease Severity Score and clinical lab parameters–TC,DC, ESR, AEC and IgE pre and post treatment.
RESULTS AND DISCUSSION: The results will be statistically analysed.
KEYWORDS:
Neer peenisam, Sinusitis, Seenthil chooranam , vetiver thailam
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 14.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Headache / sneezing/nasal congestion/ rhinorrhea/ postnasaldrip/ facial pain/ anosmia.
- •2.Pain and tenderness over paranasal sinuses.
- •3.Patient who has Adelaide Disease Severity Score above
- •4.Patients who are willing to give informed consent.
- •5.Adults who are already diagnosed with sinusitis are included.
排除标准
- •â€¢ K/C/O Migraine.
- •â€¢ Patients who have tumours in PNS X-ray • Pregnancy and lactating mother.
- •â€¢ Patients with uncontrolled Diabetes.
- •â€¢ Patients who are not willing to participate in the study will be excluded from the study.
结局指标
主要结局
The outcome will be mainly assessed by reduction in clinical symptoms after the
时间窗: 18 months
treatment by using Adelaide Disease severity score below 12
时间窗: 18 months
次要结局
- To observe changes in clinical lab parameters–TC, DC, ESR, AEC & IgE pre and post treatment(18 months)