Effects of large volume, isotonic nasal saline irrigation for acute rhinosinusitis: a randomized controlled study

Completed

• Conditions: Acute rhinosinusitis patients, adult (age 18 and over); irrigation; saline; rhinosinusitis; treatment outcome; Nasal patency; quality of life

• Registration Number: TCTR20200616001
• Lead Sponsor: Rajavithi Hospital

Brief Summary

The add-on isotonic nasal saline irrigation using a large volume, positive pressure device did not add benefits equally for all ARS patients. The benefits of irrigation on quality of life and nasal symptoms were only observed in the common cold patient subgroup.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-06-16
• Study Completion: 2020-10-01
• Results First Posted: 2021-05-07
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

age 18 and over
-diagnosis of acute rhinosinusitis

Exclusion Criteria

-actively taking anti-allergy or corticosteroid medications
-history of previous sinus surgery
-history and current evidence of nasal or paranasal sinus neoplasm
-suspected or presence of sinusitis complication
-mental disorder
-inability to communication in Thai (both read and speak)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality of life 0, 7,14 days SNOT22,Rhinologic subscore of SNOT22 0,7,14 days SNOT22,Nasal symptom score 0,7,14 days Combined nasal symptom visual analog scale

Secondary Outcome Measures

Name	Time	Method
Cure rate 0,7,14 improve symptoms on SNOT-22 and endoscopy,adverse event 0,7,14 days self report of adverse event,Endoscopy 0,7,14 days Modified Lund Kennedy Endoscopic Score