Effects of Inspiratory Muscle Training in Addition to Pulmonary Rehabilitation in Patients With COPD Exacerbation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Exacerbation Copd
- Sponsor
- National Taiwan University Hospital
- Enrollment
- 16
- Locations
- 1
- Primary Endpoint
- Sternocleidomastoid muscle activation
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Inspiratory muscle weakness, limited functional exercise capacity and worse quality of life have been shown in patients with exacerbation of chronic obstructive pulmonary disease (COPD). Recommendations from clinical practice guideline state that promoting pulmonary rehabilitation after exacerbation can improve the conditions above. Inspiratory muscle training (IMT) has been proven to enhance inspiratory muscle strength and endurance in patient with stable COPD. However, there is less research on whether IMT in addition to pulmonary rehabilitation after exacerbation can benefit inspiratory muscle function, functional exercise capacity and quality of life in patients with COPD. The purpose of this study is to examine the effects of IMT in addition to pulmonary rehabilitation on respiratory muscle function, functional exercise capacity and quality of life in patients with exacerbation of chronic obstructive pulmonary disease.
Investigators
Eligibility Criteria
Inclusion Criteria
- •age \> 20 years old
- •diagnosed as exacerbation of COPD
- •maximal inspiratory pressure (MIP) \< 80 cmH2O
Exclusion Criteria
- •any clinical diagnosis that will influence the measurement, including any history of neuromyopathy
- •angina, acute myocardial infarction in the previous one month
- •pregnancy
- •participated in inspiratory muscle training program in the previous three months
- •any psychiatric or cognitive disorders, for example: Mini-Mental State Examination (MMSE) \< 24, that will disturb the communication and cooperation of the study
Outcomes
Primary Outcomes
Sternocleidomastoid muscle activation
Time Frame: 10 minutes
The surface electromyography (EMG) signal was analyzed in the time domain, calculating root mean square (RMS) amplitude with a time constant of 30 mini seconds. A 1.5 seconds window of SCM muscle signals at peak pressure during maximal inspiratory pressure test were obtained and calculated as maximal effort. SCM activation were calculated using mean RMS values of each threshold loaded breathing test, and then normalized to maximal effort (%EMGSCM).
Diaphragm muscle activation
Time Frame: 10 minutes
The surface electromyography (EMG) signal was analyzed in the time domain, calculating root mean square (RMS) amplitude with a time constant of 30 mini seconds. A 1.5 seconds window of diaphragm muscle signals at peak pressure during maximal inspiratory pressure test were obtained and calculated as maximal effort. Diaphragm activation were calculated using mean RMS values of each threshold loaded breathing test, and then normalized to maximal effort (%EMGDia).
Secondary Outcomes
- The mean median frequency of diaphragm and sternocleidomastoid muscle(10 minutes)
- Quality of life evaluation(10 minutes)
- Functional exercise capacity(Considering time of test and recovery, it will be expected to take totally 10 minutes.)