United Coronary Biobanks

Completed

• Conditions: Myocardial Infarction; Coronary Artery Disease; Stable Angina; Acute Coronary Syndrome

• Registration Number: NCT02126150
• Lead Sponsor: UMC Utrecht

Brief Summary

The UNICORN consists of two collaborating biobanks, one in Utrecht and one in Singapore. From these two sites we include all patients who undergo a coronary catheterization for any reason.

At the moment of catheterization we draw blood, which will be stored in a biobank and we collect clinical characteristics. Patients are followed-up for 5 years for the occurrence of major cardiovascular events.

By including from two sites in the world we include 4 major ethnic groups: Caucasians, Chinese, Indians and Malays. We aim at including at least 2000 patients per ethnic group.

Our hypothesis is that there are differences in the risk factor burden, clinical presentation of CAD, and biochemical patterns in the blood among the ethnic groups.

Furthermore, this biobank offers a platform for multi-ethnic biomarker discovery.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-09
• Study First Submitted: 2014-04-24
• Study First Submitted QC: 2014-04-28
• Study First Posted: 2014-04-29
• Status Verified: 2015-12
• Primary Completion: 2015-12
• Study Completion: 2015-12
• Last Update Submitted: 2015-12-07
• Last Update Posted: 2015-12-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

• Patients undergoing coronary angiography

Exclusion Criteria

• < 21 years of age
• Hemoglobin levels <7 g/dL in women, or hemoglobin levels <8 g/dL in men

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
All-cause death	5 years

Secondary Outcome Measures

Name	Time	Method
Major cardiovascular events	5 years

Trial Locations

Locations (1)

National University Hospital; 🇸🇬 Singapore, Singapore