Respiratory Support and Treatment for Efficient and Cost-Effective Care
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 362
- 试验地点
- 2
- 主要终点
- HFNC duration
研究概览
简要总结
This project aims to answer the essential questions about the management of acute, pediatric respiratory illness, accelerate recovery from these all-too-common diseases, curb unnecessary costs of care, and demonstrate UPMC Children's Hospital of Pittsburgh's capabilities as the premier, world-class leader in the arena of pediatric learning healthcare systems. REST EEC will focus on the question of whether clinical decision support (CDS) facilitates the standardization of the initiation and weaning of heated high flow nasal cannula (HHFNC) for bronchiolitis.REST EEC will focus on whether the application of CDS improves adherence to a standardized guideline and leads to improved patient-centered outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- — 至 2 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •<2 years of age Bronchiolitis WOB Score >2
排除标准
- •Immunocompromised
- •Immunosuppressed
- •Chronic lung disease
- •Congenital heart disease with baseline cardiorespiratory manifestations
研究组 & 干预措施
HHFNC Weaning
Team does not receive clinical decision support reminders to wean the HHFNC
干预措施: HHFNC Weaning (Device)
HHFNC + Clinical decision Support
Standardized HHFNC weaning coupled with clinical decision support consisting of electronic record embedded reminders to the clinical team to wean HHFNC
干预措施: Clinical Decision Support (CDS) (Other)
HHFNC + Clinical decision Support
Standardized HHFNC weaning coupled with clinical decision support consisting of electronic record embedded reminders to the clinical team to wean HHFNC
干预措施: HHFNC Weaning (Device)
HHFNC Weaning
Team does not receive clinical decision support reminders to wean the HHFNC
干预措施: Clinical Decision Support (CDS) (Other)
结局指标
主要结局
HFNC duration
时间窗: Timeframe consists of a start time of either randomization or the last documentation of positive pressure ventilation (whichever is later) and the last documentation of HFNC in the electronic flowsheet, up to 30 days
Amount of time patient is on HFNC
次要结局
- Organ support free days(From date of admission until the first day of ICU-based respiratory or cardiovascular organ support or discharge or date of death from any case, whichever came first, assessed up to 30 days)
- Respiratory support free days(From date the start of respiratory support until the first documented respiratory support free day, up to 30 days)
- PICU length of stay(From data of admission to PICU to discharge from the PICU or death from any cause, whichever came first, assessed up to 90 days.)
- Hospital length of stay(From date of admission until discharge or date of death from any cause, whichever came first, assessed up to 90 days.)
- Time to oral intake(From date of ending HHFNC until first documented oral intake, assessed up to 30 days)
- Cost of hospitalization(Days from admission to discharge from hospital or date of death, up to 90 days. Of note, an earlier outcome was listed for 90-day cost of care and the redundancy with this outcome was recognized, so the 90-day cost of care outcome was removed.)
- Mortality(From date of admission until death from any cause, assessed up to 90 days)
- Ostensible respiratory distress measured by a respiratory severity score(Through study completion, an average of 1 week)
研究者
Christopher Horvat
Assistant Professor
University of Pittsburgh