Acupuncture Treatment for Improving Alzheimer's Dementia

Not Applicable

Withdrawn

• Conditions: Cognitive Deficits; Alzheimer Disease
• Interventions: Procedure: Acupunture

• Registration Number: NCT04064021
• Lead Sponsor: N & S Neurology Center, A Medical Group, Inc

Brief Summary

Evaluate cognitive improvement pre amd post acupuncture treatment in patients with probable alzheimer's dementia as measured by MOCA score and also per form A( measure of patient's personal information). Also caregiver input.

Detailed Description

Patient's with diagnosis of probable mild to moderate AD will be enrolled in this study. Patient will undergo neurological examination including MOCA. Examiner will also fill out Form A at the time of initial evaluation.

Patient will then undergo series of acupuncture treatments 2 per week for 6 weeks(12 acupuncture treatment). At end of this intervention patients will be reassessed using same testing(MOCA and form A) Data collected will be assessed via statistical analysis to see if there is any statistically significant improvement.

Acupuncture points used in this trial will stay the same for all subjects and throughout the course. The points will be Si Shen Chong, ST36, 37, LV 2,3,6, GB 34, 39, Xia San Huang, LI 11, LI 4.

Study Timeline

• Study First Submitted: 2015-04-28
• Study First Submitted QC: 2019-08-19
• Study First Posted: 2019-08-21
• Status Verified: 2022-10
• Last Update Submitted: 2022-10-07
• Last Update Posted: 2022-10-12
• Study Start: 2025-01-01
• Primary Completion: 2026-12-31
• Study Completion: 2027-03-31

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Mild to moderate AD

Exclusion Criteria

• Severe AD

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Acupuncture	Acupunture	Acupuncture 12 sessions over 6 week to be given to pateints

Primary Outcome Measures

Name	Time	Method
Improvement on Montreal Cognitive Assessment test of 5 points or more than baseline( total score is out of 30 points)	12 weeks	Subject will complete 3 MOCA assessment prior to study over 1 week time. Best score of three is used.; After study is complete subject will also undergo 3 MOCA assessment over 1 week immediately after study. Again best score is used.

Secondary Outcome Measures

Name	Time	Method
Improvement of Montreal Cognitive Assessment test by category than raw total score	12 weeks	performance on various subcategory will also be reviewed to see if one category improves over other category. (Example: Visual-spacial parameters improves over language)