A Prospective Multicenter Study to Evaluate Usefulness of Cardio-Ankle Vascular Index in Japan

CAVI-J Study Group1 site in 1 country3,026 target enrollmentMay 2013

ConditionsStroke Cardiovascular Death Nonfatal Myocardial Infarction

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Stroke
Sponsor: CAVI-J Study Group
Enrollment: 3026
Locations: 1
Primary Endpoint: major cardiac events
Status: Completed
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The objective of this five-year prospective observational follow-up study is to examine the additional benefits of using cardio-ankle vascular index (CAVI) as a predictive indicator of cardiovascular events in high-risk patients.

Registry

clinicaltrials.gov

Start Date

May 2013

End Date

April 2020

Last Updated

5 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

CAVI-J Study Group

Responsible Party

Sponsor Investigator

Principal Investigator

CAVI-J Study Group

CAVI-J study Group

Okayama University

Eligibility Criteria

Inclusion Criteria

•Patients between 40 and 74 years of age who have either of the following:
•Type 2 diabetes mellitus
•Metabolic syndrome
•Grade I to III hypertension with the third layer of risk factors according to the guidelines for the management of hypertension japanese society of hypertension(JSH)2009
•Chronic kidney disease(stage G3a or G3b) according ot the clinical Practice Guidebook for Diagnosis and Treatment of Chronic Kidney Disease 2012 in Japan
•History of coronary artery disease or noncardiogenic cerebral infarction

Exclusion Criteria

•Under 40 years of age or over 74 years of age
•An ankle-brachial index less than 0.9
•Chronic atrial fibrillation
•Current symptoms of heart failure(NYHA class III or IV) or left ventricular dysfunction (EF below 40%)
•Chronic kidney disease(G4 or G5)according ot the clinical Practice Guidebook for Diagnosis and Treatment of Chronic Kidney Disease 2012 in Japan
•chronic dialysis due to renal failure
•Taking steroids/immunosuppressants
•Hepatocirrhosis