“Study of pain syndrome and clinical-biochemical parameters in children aged 7 to 18 years in cases of non-surgical treatment of uncomplicated acute appendicitis”

Not yet recruiting

• Conditions: uncomplicated acute appendicitis

• Registration Number: 2025-520964-16-00
• Lead Sponsor: Riga Stradins University

Brief Summary

To perform a study of pain syndrome and clinical-biochemical

parameters in 7 to 18 years old children with uncomplicated acute

appendicitis in non-surgical treatment and develop an analgesic

algorithm based on the obtained data.

Detailed Description

Not available

Study Timeline

• Study First Posted: 2025-01-30
• Last Update Posted: 2025-01-30

Recruitment & Eligibility

• Status: Authorised, recruitment pending
• Sex: Not specified
• Target Recruitment: 120

Inclusion Criteria

7 to 18 years old children with first time diagnosed uncomplicated acute appendicitis who received non-surgical treatment.

Exclusion Criteria

Psychomotor retardation of any degree; Any inherited or acquired immunodeficiency; Any abdominal surgery in medical history; Neurological deficit of any degree; Any endocrine disease; NSAID use within 3 hours; Chronic pain requiring daily analgesic use; History of gastrointestinal bleeding, peptic or duodenal ulcer disease or inflammatory bowel disease, coagulation disorders, prior cerebrovascular bleeding, known arterio-vascular malformations; History of chronic and active renal disease, excluding renal calculi and urinary tract infections; History of chronic and active hepatocellular disease (excludes biliary stones, cholangitis or biliary duct pathology); Known hypersensitivity to ketorolac (or it's component) or other NSAID; Absence of a parent/guardian for children who are < 14 years in age.

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of patients consented from total approached; Number of patients who completed pain assessment and treatment at all time points (totally for 3 days (72 hours));		Number of patients consented from total approached; Number of patients who completed pain assessment and treatment at all time points (totally for 3 days (72 hours));

Trial Locations

Locations (1)

Bernu Kliniska Universitates Slimnica VSIA; 🇱🇻 Riga, Latvia

Bernu Kliniska Universitates Slimnica VSIA

🇱🇻Riga, Latvia

Jurijs Bormotovs

Site contact

26324310

jurijs.bormotovs@bkus.lv